Literature DB >> 785430

Use of temperature-sensitive mutants of influenza A virus as live virus vaccine strains. Evaluation in laboratory animals, adults and children.

B R Murphy, D D Richman, S B Spring, R M Chanock.   

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Year:  1976        PMID： 785430      PMCID： PMC2496312          DOI： 10.1136/pgmj.52.608.381

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


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  18 in total

1.  Temperature sensitive mutants of influenza virus. IX. Genetic and biological characterization of TS-1[E] lesions when transferred to a 1972 (H3N2) influenza A virus.

Authors:  D D Richman; B R Murphy; S B Spring; M T Coleman; R M Chanock
Journal:  Virology       Date:  1975-08       Impact factor: 3.616

2.  Temperature-sensitive mutants of influenza. VIII. Genetic and biological characterization of TS mutants of influenza virus A (H3N2) and their assignment to complementation groups.

Authors:  S B Spring; S R Nusinoff; E L Tierney; D D Richman; B R Murphy; R M Chanock
Journal:  Virology       Date:  1975-08       Impact factor: 3.616

3.  Temperature-sensitive mutants of influenza virus. VI. Transfer of TS lesions from the Asian subtype of influenza A virus (H2N2) to the Hong Kong subtype (H3N2).

Authors:  S B Spring; S R Nusinoff; J Mills; D D Richman; E L Tierney; B R Murphy; R M Chanock
Journal:  Virology       Date:  1975-08       Impact factor: 3.616

4.  Temperature-Sensitive mutants of influenza virus. VII. Transfer of the TS-1[E] lesions to a wild-type influenza A virus with the HON1 surface antigens.

Authors:  B R Murphy; S B Spring; D D Richman; E L Tierney; J Kasel; R M Chanock
Journal:  Virology       Date:  1975-08       Impact factor: 3.616

5.  The Seattle virus watch. IV. Comparative epidemiologic observations of infections with influenza A and B viruses, 1965-1969, in families with young children.

Authors:  C E Hall; M K Cooney; J P Fox
Journal:  Am J Epidemiol       Date:  1973-11       Impact factor: 4.897

6.  Mechanism of influenza recombination. I. Factors influencing recombination rates between temperature-sensitive mutants of strain WSN and the classification of mutants into complementation--recombination groups.

Authors:  G K Hirst
Journal:  Virology       Date:  1973-09       Impact factor: 3.616

7.  Temperature-sensitive mutants of influenza virus. V. Evaluation in man of an additional ts recombinant virus with a 39 C shutoff temperature.

Authors:  B R Murphy; D S Hodes; S R Nusinoff; S Spring-Stewart; E L Tierney; R M Chanock
Journal:  J Infect Dis       Date:  1974-08       Impact factor: 5.226

8.  A Hong Kong influenza immunity three years after immunization.

Authors:  H M Foy; M K Cooney; R McMahan
Journal:  JAMA       Date:  1973-11-12       Impact factor: 56.272

9.  Temperature-sensitive mutants of influenza virus. II. Attenuation of ts recombinants for man.

Authors:  B R Murphy; E G Chalhub; S R Nusinoff; R M Chanock
Journal:  J Infect Dis       Date:  1972-08       Impact factor: 5.226

10.  Temperature-sensitive mutants of influenza virus. 3. Further characterization of the ts-1(E) influenza A recombinant (H3N2) virus in man.

Authors:  B R Murphy; E G Chalhub; S R Nusinoff; J Kasel; R M Chanock
Journal:  J Infect Dis       Date:  1973-10       Impact factor: 5.226
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  12 in total

1.  Biochemistry and pathogenicity of echovirus 9. III. Thermosensitive mutants of echovirus 9, strain Barty, with reduced pathogenicity for newborn mice.

Authors:  B Rosenwirth; D Ziegenhagen; H J Eggers
Journal:  Med Microbiol Immunol       Date:  1988       Impact factor: 3.402

2.  Prospects for new vaccines.

Authors:  A J Beale
Journal:  Postgrad Med J       Date:  1976-09       Impact factor: 2.401

3.  Temperature-sensitive mutants of influenza A virus: evaluation of the Alaska/77-ts-1A2 temperature-sensitive recombinant virus in seronegative adult volunteers.

Authors:  B R Murphy; R M Chanock; R G Douglas; R F Betts; D H Waterman; H P Holley; D L Hoover; S Suwanagool; D R Nalin; M M Levine
Journal:  Arch Virol       Date:  1980       Impact factor: 2.574

4.  Cold adapted variants of influenza A. II. Comparison of the genetic and biological properties of ts mutants and recombinants of the cold adapted A/AA/6/60 strain.

Authors:  S B Spring; H F Maassab; A P Kendal; B R Murphy; R M Chanock
Journal:  Arch Virol       Date:  1977       Impact factor: 2.574

5.  Temperature-sensitive mutants of influenza A virus: production and characterization of A/Victoria/3/75-ts-1[E] recombinants.

Authors:  B R Murphy; N T Hosier; S B Spring; S R Mostow; R M Chanock
Journal:  Infect Immun       Date:  1978-06       Impact factor: 3.441

6.  Temperature-sensitive mutants of influenza A virus. Transfer of the two ts-1A2 ts lesions present in the Udorn/72-ts-1A2 donor virus to the influenza A/Alaska/6/77 (H3N2) wild type virus.

Authors:  B R Murphy; F T Wood; J G Massicot; R M Chanock
Journal:  Arch Virol       Date:  1980       Impact factor: 2.574

7.  Use of the enzyme-linked immunosorbent assay to detect serum antibody responses of volunteers who received attenuated influenza A virus vaccines.

Authors:  B R Murphy; E L Tierney; B A Barbour; R H Yolken; D W Alling; H P Holley; R E Mayner; R M Chanock
Journal:  Infect Immun       Date:  1980-08       Impact factor: 3.441

8.  Temperature-sensitive mutants of influenza A virus: transfer of the two temperature-sensitive lesions in the Udorn/72-ts-1A2 virus to the A2Hong Kong/123/77 (H1N1) wild-type virus.

Authors:  B R Murphy; N T Hosier; R M Chanock
Journal:  Infect Immun       Date:  1980-06       Impact factor: 3.441

9.  Relationship of genotype of recombinants of influenza A/Hong Kong/68-ts-1[E]virus used as live virus vaccines to virulence in humans.

Authors:  L J Markoff; F Thierry; B R Murphy; R M Chanock
Journal:  Infect Immun       Date:  1979-10       Impact factor: 3.441

10.  Behavior of vaccine revertants of temperature-sensitive mutants of influenza virus in ferret tracheal organ culture.

Authors:  S R Mostow; J A Hopkins; P F Wright
Journal:  Infect Immun       Date:  1979-10       Impact factor: 3.441
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