J C Culberson1, B L Bush, V V Sardana. Show Affiliations » 1. Department of Molecular Systems, Merck Research Laboratories, West Point, Pennsylvania 19486.
Abstract
Mesh： See more » Amino Acid SequenceAntiviral Agents/chemistryAntiviral Agents/pharmacologyAspartic Acid Endopeptidases/antagonists & inhibitorsAspartic Acid Endopeptidases/chemistryAspartic Acid Endopeptidases/geneticsBinding SitesComputer SimulationDrug Resistance, MicrobialHIV Protease/chemistryHIV Protease/geneticsHIV Protease Inhibitors/chemistryHIV Protease Inhibitors/pharmacologyHIV-1/drug effectsHIV-1/enzymologyHIV-2/drug effectsHIV-2/enzymologyModels, MolecularMolecular Sequence DataMutagenesis, Site-DirectedProtein BindingProtein ConformationRetroviridae/drug effectsRetroviridae/geneticsRetroviridae Proteins/antagonists & inhibitorsRetroviridae Proteins/chemistryRetroviridae Proteins/geneticsSoftwareSubstrate Specificity
Substances： See more » Antiviral AgentsHIV Protease InhibitorsRetroviridae ProteinsAspartic Acid EndopeptidasesHIV Proteasep16 protease, Human immunodeficiency virus 2
Year: 1994 PMID： 7854190 DOI： 10.1016/0076-6879(94)41075-5
Source DB: PubMed Journal: Methods Enzymol ISSN： 0076-6879 Impact factor: 1.600