Literature DB >> 7853533

Localization of monoclonal antibody epitopes and functional domains in the hemagglutinin protein of measles virus.

K B Hummel1, W J Bellini.   

Abstract

The expression of chimeric proteins was performed for the localization of monoclonal antibody (MAb) epitopes and functional domains in the hemagglutinin (H) protein of measles virus. The fusion helper function of the H protein was ablated by a single amino acid substitution at residue 98. Loss of reactivity to MAb 79-XV-V17 and to MAbs 16-CD-11 and 80-II-B2 was attributed to substitutions between residues 211 and 291 and between 451 and 505, respectively. The 80-II-B2 MAb epitope also seemed to be within a domain required for hemadsorption and hemagglutination activities.

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Year:  1995        PMID： 7853533      PMCID： PMC188806     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  33 in total

1.  Differences in bovine parainfluenza 3 virus variants studied by sequencing of the genes of viral envelope proteins.

Authors:  T Shioda; S Wakao; S Suzu; H Shibuta
Journal:  Virology       Date:  1988-02       Impact factor: 3.616

2.  Characterization of epitopes on the measles virus hemagglutinin.

Authors:  H Sheshberadaran; E Norrby
Journal:  Virology       Date:  1986-07-15       Impact factor: 3.616

3.  Antigenicity of the measles virus haemagglutinin studied by using synthetic peptides.

Authors:  M J Mäkelä; G A Lund; A A Salmi
Journal:  J Gen Virol       Date:  1989-03       Impact factor: 3.891

4.  Characterization of CR1- and membrane cofactor protein-like proteins of two primates.

Authors:  M W Nickells; J P Atkinson
Journal:  J Immunol       Date:  1990-06-01       Impact factor: 5.422

5.  A new generation of animal cell expression vectors based on the Semliki Forest virus replicon.

Authors:  P Liljeström; H Garoff
Journal:  Biotechnology (N Y)       Date:  1991-12

6.  Idiotypes and biological activity of murine monoclonal antibodies against the hemagglutinin of measles virus.

Authors:  J Gheuens; D E McFarlin; K W Rammohan; W J Bellini
Journal:  Infect Immun       Date:  1981-10       Impact factor: 3.441

7.  Fusion properties of cells persistently infected with human parainfluenza virus type 3: participation of hemagglutinin-neuraminidase in membrane fusion.

Authors:  A Moscona; R W Peluso
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

8.  Correlation between epitopes on hemagglutinin of measles virus and biological activities: passive protection by monoclonal antibodies is related to their hemagglutination inhibiting activity.

Authors:  P Giraudon; T F Wild
Journal:  Virology       Date:  1985-07-15       Impact factor: 3.616

9.  Functional interactions between the fusion protein and hemagglutinin-neuraminidase of human parainfluenza viruses.

Authors:  X L Hu; R Ray; R W Compans
Journal:  J Virol       Date:  1992-03       Impact factor: 5.103

10.  Measles virus: both the haemagglutinin and fusion glycoproteins are required for fusion.

Authors:  T F Wild; E Malvoisin; R Buckland
Journal:  J Gen Virol       Date:  1991-02       Impact factor: 3.891
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  15 in total

1.  Sequence and structure alignment of Paramyxoviridae attachment proteins and discovery of enzymatic activity for a morbillivirus hemagglutinin.

Authors:  J P Langedijk; F J Daus; J T van Oirschot
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

2.  Measles virus assembly within membrane rafts.

Authors:  S Vincent; D Gerlier; S N Manié
Journal:  J Virol       Date:  2000-11       Impact factor: 5.103

3.  Structure of the measles virus hemagglutinin bound to the CD46 receptor.

Authors:  César Santiago; María L Celma; Thilo Stehle; José M Casasnovas
Journal:  Nat Struct Mol Biol       Date:  2009-12-13       Impact factor: 15.369

4.  Spontaneous mutation rate of measles virus: direct estimation based on mutations conferring monoclonal antibody resistance.

Authors:  S J Schrag; P A Rota; W J Bellini
Journal:  J Virol       Date:  1999-01       Impact factor: 5.103

5.  Identification of two amino acids in the hemagglutinin glycoprotein of measles virus (MV) that govern hemadsorption, HeLa cell fusion, and CD46 downregulation: phenotypic markers that differentiate vaccine and wild-type MV strains.

Authors:  V Lecouturier; J Fayolle; M Caballero; J Carabaña; M L Celma; R Fernandez-Muñoz; T F Wild; R Buckland
Journal:  J Virol       Date:  1996-07       Impact factor: 5.103

6.  Recombinant measles viruses expressing altered hemagglutinin (H) genes: functional separation of mutations determining H antibody escape from neurovirulence.

Authors:  K Moeller; I Duffy; P Duprex; B Rima; R Beschorner; S Fauser; R Meyermann; S Niewiesk; V ter Meulen; J Schneider-Schaulies
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

7.  Identification of immunodominant neutralizing epitopes on the hemagglutinin protein of rinderpest virus.

Authors:  Makoto Sugiyama; Naoto Ito; Nobuyuki Minamoto; Seiichi Tanaka
Journal:  J Virol       Date:  2002-02       Impact factor: 5.103

8.  Multiple amino acid substitutions in hemagglutinin are necessary for wild-type measles virus to acquire the ability to use receptor CD46 efficiently.

Authors:  Maino Tahara; Makoto Takeda; Fumio Seki; Takao Hashiguchi; Yusuke Yanagi
Journal:  J Virol       Date:  2006-12-20       Impact factor: 5.103

9.  The receptor-binding site of the measles virus hemagglutinin protein itself constitutes a conserved neutralizing epitope.

Authors:  Maino Tahara; Shinji Ohno; Kouji Sakai; Yuri Ito; Hideo Fukuhara; Katsuhiro Komase; Melinda A Brindley; Paul A Rota; Richard K Plemper; Katsumi Maenaka; Makoto Takeda
Journal:  J Virol       Date:  2013-01-02       Impact factor: 5.103

10.  Importance of the cytoplasmic tails of the measles virus glycoproteins for fusogenic activity and the generation of recombinant measles viruses.

Authors:  Markus Moll; Hans-Dieter Klenk; Andrea Maisner
Journal:  J Virol       Date:  2002-07       Impact factor: 5.103
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