Neurobehavioral changes following bilateral infarct in the caudate nuclei: a case report with pathological analysis.

A patient presenting with loss of psychic self activation (LPSA) was studied clinically and at autopsy. Clinically, the patient showed changes that can be ascribed to the interruption of frontal-subcortical circuits. Pathological analysis revealed bilateral lesions of the caudate nuclei. This case extends others based on radiological findings and confirms the importance of the caudate nuclei in behavioral functions.