Literature DB >> 7853009

Inhibitors of protein tyrosine kinase pp60v-src: sterol sulfates from the brittle star Ophiarachna incrassata.

X Fu1, F J Schmitz, R H Lee, J S Papkoff, D L Slate.   

Abstract

Bioactivity-guided fractionation of the extracts of the green brittle star Ophiarachna incrassata using a protein tyrosine kinase pp60v-src inhibition assay led to the isolation of a new sterol sulfate [2] together with four known ones (1,3-5). All five compounds were found to inhibit protein tyrosine kinase pp 60v-src.

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Year:  1994        PMID： 7853009     DOI： 10.1021/np50113a023

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  2 in total

1.  Synthesis and antiviral activity of sulfated and acetylated derivatives of 2beta,3alpha-dihydroxy-5alpha-cholestane.

Authors:  Gustavo A Garrido Santos; Ana P Murray; Carlos A Pujol; Elsa B Damonte; Marta S Maier
Journal:  Steroids       Date:  2003-02       Impact factor: 2.668

2.  Disulfated Ophiuroid Type Steroids from the Far Eastern Starfish Pteraster marsippus and Their Cytotoxic Activity on the Models of 2D and 3D Cultures.

Authors:  Alla A Kicha; Anatoly I Kalinovsky; Timofey V Malyarenko; Olesya S Malyarenko; Svetlana P Ermakova; Roman S Popov; Valentin A Stonik; Natalia V Ivanchina
Journal:  Mar Drugs       Date:  2022-02-24       Impact factor: 5.118
  2 in total

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