| Literature DB >> 78523 |
Abstract
Kepone induces ovalbumin and conalbumin synthesis in explants of chick oviduct in vitro by acting as a weak estrogen. It binds to the nuclear estrogen receptor and is antagonized by the antiestrogen tamoxifen. Kepone also induces egg white protein synthesis in vivo by direct interaction with estrogen receptors and by indirectly increasing the concentration of progesterone in the serum.Entities:
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Year: 1978 PMID: 78523 DOI: 10.1126/science.78523
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728