Literature DB >> 7851827

[An in-vitro study of 2 resins used in orthodontics for their cell toxicity].

A Zentner1, H G Sergl, A Kretschmer.   

Abstract

The aim of this study was to examine in vitro cell compatibility of the orthodontic base resins Orthocryl (Dentaurum) and Wil-o-dont (Wilde) using the method described by Heidemann and Lampert (1980). The acute local nonspecific cytotoxicity of these materials and that of their individual components were evaluated. Used were both a qualitative microscopic assessment of cytopathological changes occurring in human gingival fibroblasts cultured along side the specimens and a semiquantitative assessment of the zones of inhibited cell growth around the specimens. Whereas Orthocryl and its components exhibited no toxic influence on the growth of the cultured cells, substantial cytotoxicity was observed in the tests of Wil-o-dont. The monomer and the adhesive component of this resin were found to be particularly toxic under the conditions tested. On the basis of the results of the study Wil-o-dont can not be given a clean bill of health in relation to the cytotoxicity of the product.

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Year:  1994        PMID: 7851827     DOI: 10.1007/bf02285419

Source DB:  PubMed          Journal:  Fortschr Kieferorthop        ISSN: 0015-816X


  8 in total

1.  [The testing of the toxicity of the plastics used in orthodontics].

Authors:  K U Schendel; M Lenhardt; N E Fusenig; G Komposch
Journal:  Fortschr Kieferorthop       Date:  1992-10

Review 2.  [Biocompatibility of dental materials: Part 2. Materials with mucosal contact].

Authors:  W T Klötzer; N Reuling
Journal:  Dtsch Zahnarztl Z       Date:  1990-08

Review 3.  [Limits of biocompatibility testing of dental materials in cell culture].

Authors:  W T Klötzer
Journal:  Quintessenz       Date:  1988-12

4.  [DIN-Standard 13930: biological testing of dental materials. II: Application tests. Comparable standards].

Authors:  W T Klötzer; G Schmalz
Journal:  Dtsch Zahnarztl Z       Date:  1986-12

Review 5.  Use of cell cultures for toxicity testing of dental materials--advantages and limitations.

Authors:  G Schmalz
Journal:  J Dent       Date:  1994       Impact factor: 4.379

6.  [Correlation analyses between cell cultures and animal experiments].

Authors:  G Schmalz
Journal:  Dtsch Zahnarztl Z       Date:  1982-02

7.  [Human gingiva in cell culture].

Authors:  D Heidemann; F Lampert
Journal:  Dtsch Zahnarztl Z       Date:  1980-03

8.  [Processing and evaluation of orthodontic autopolymerizing agents].

Authors:  B Rossiwall; H Newesely; R Bartels
Journal:  Fortschr Kieferorthop       Date:  1984-10
  8 in total
  2 in total

1.  Assessment of acute cyto- and genotoxicity of corrosion eluates obtained from orthodontic materials using monolayer cultures of immortalized human gingival keratinocytes.

Authors:  P Tomakidi; U Koke; R Kern; L Erdinger; H Krüger; A Kohl; G Komposch
Journal:  J Orofac Orthop       Date:  2000       Impact factor: 1.938

2.  Influence of Test Specimen Geometry and Water Soaking on the In Vitro Cytotoxicity of Orthocryl®, Orthocryl® LC, Loctite® EA 9483 and Polypropylene.

Authors:  Richard Behnke; Franka Stahl; Kathrin Duske; Mareike Warkentin; Margit Schwartz; Burkhard Hinz; Udo Walther
Journal:  Molecules       Date:  2022-06-20       Impact factor: 4.927

  2 in total

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