Literature DB >> 7850475

On the mechanism of antiepileptic peptides appearance in the cerebrospinal fluid.

A A Shandra1, L S Godlevsky, A M Mazarati, A V Panenko, I V Tkachenko, Y P Chirkov.   

Abstract

Intraventricular injection of cerebrospinal fluid obtained from cats with electroshock seizures resulted in suppression of generalized picrotoxin-induced seizures in rats. Antiepileptic action of cerebrospinal fluid was abolished by partial bilateral midbrain destruction that included the region of colliculi superii. Electrical stimulation of cerebellum in cats with such destructions caused the appearance of a pronase-sensitive antiepileptic substances in cerebrospinal fluid.

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Year:  1994        PMID： 7850475     DOI： 10.1016/0361-9230(94)90102-3

Source DB:  PubMed          Journal:  Brain Res Bull        ISSN： 0361-9230            Impact factor:   4.077


  2 in total

1.  Delta-sleep-inducing peptide and its analogs and the serotoninergic system in the development of anticonvulsive influences.

Authors:  A A Shandra; L S Godlevskii; A I Brusentsov; V P Petrashevich; R S Vast'yanov; B Nikel; I I Mikhaleva
Journal:  Neurosci Behav Physiol       Date:  1998 Sep-Oct

2.  The effects of electrical stimulation of the paleocerebellar cortex on penicillin-induced convulsive activity in rats.

Authors:  L S Godlevskii; K I Stepanenko; B A Lobasyuk; E V Sarakhan; L M Bobkova
Journal:  Neurosci Behav Physiol       Date:  2004-10
  2 in total

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