OBJECTIVE: To examine the safety and efficacy of fluconazole in patients with a permanent nephrostomy or suprapubic catheter in the prevention of candiduria. PATIENTS AND METHODS: Twenty patients with a nephrostomy or suprapubic catheter who had at least two positive urine cultures with a minimum of 15,000 col/mL Candida counts were studied. The catheters were irrigated with fluconazole solution prepared as 1 mg/mL with normal saline. Repeated urine cultures were obtained. RESULTS: In 17 patients Candida was eradicated from the urine by the third to sixth day of irrigation. No side-effects were noted. CONCLUSION: Fluconazole as an irrigant is effective and safe in the treatment of catheter-associated candiduria, which can be eliminated without changing the catheter.
OBJECTIVE: To examine the safety and efficacy of fluconazole in patients with a permanent nephrostomy or suprapubic catheter in the prevention of candiduria. PATIENTS AND METHODS: Twenty patients with a nephrostomy or suprapubic catheter who had at least two positive urine cultures with a minimum of 15,000 col/mL Candida counts were studied. The catheters were irrigated with fluconazole solution prepared as 1 mg/mL with normal saline. Repeated urine cultures were obtained. RESULTS: In 17 patients Candida was eradicated from the urine by the third to sixth day of irrigation. No side-effects were noted. CONCLUSION:Fluconazole as an irrigant is effective and safe in the treatment of catheter-associated candiduria, which can be eliminated without changing the catheter.