Literature DB >> 7850211

Mycobacterium tuberculosis: drug-resistance mechanisms.

S T Cole1.   

Abstract

Tuberculosis has resurged during the past decade in many industrialized countries, and strains of Mycobacterium tuberculosis that are resistant to one or more of the main antituberculous drugs are emerging. The molecular basis of mycobacterial drug resistance is now beginning to be understood. Resistance derives from mutations in chromosomal genes leading to overproduction, alteration or loss of the drug target.

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Year:  1994        PMID： 7850211     DOI： 10.1016/0966-842x(94)90621-1

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  12 in total

1.  Altered permeability and beta-lactam resistance in a mutant of Mycobacterium smegmatis.

Authors:  S Mukhopadhyay; P Chakrabarti
Journal:  Antimicrob Agents Chemother       Date:  1997-08       Impact factor: 5.191

2.  Differential expression of sigH paralogs during growth and under different stress conditions in Mycobacterium smegmatis.

Authors:  Anirudh K Singh; Bhupendra N Singh
Journal:  J Bacteriol       Date:  2009-02-13       Impact factor: 3.490

3.  Genotypic assessment of isoniazid and rifampin resistance in Mycobacterium tuberculosis: a blind study at reference laboratory level.

Authors:  A Telenti; N Honoré; C Bernasconi; J March; A Ortega; B Heym; H E Takiff; S T Cole
Journal:  J Clin Microbiol       Date:  1997-03       Impact factor: 5.948

4.  Exposure to antibiotics induces expression of the Mycobacterium tuberculosis sigF gene: implications for chemotherapy against mycobacterial persistors.

Authors:  T M Michele; C Ko; W R Bishai
Journal:  Antimicrob Agents Chemother       Date:  1999-02       Impact factor: 5.191

5.  Characterization of a porin from Mycobacterium smegmatis.

Authors:  S Mukhopadhyay; D Basu; P Chakrabarti
Journal:  J Bacteriol       Date:  1997-10       Impact factor: 3.490

6.  Presence of katG gene in resistant Mycobacterium tuberculosis.

Authors:  M Jaber; A Rattan; R Kumar
Journal:  J Clin Pathol       Date:  1996-11       Impact factor: 3.411

7.  Thymidylate kinase of Mycobacterium tuberculosis: a chimera sharing properties common to eukaryotic and bacterial enzymes.

Authors:  H Munier-Lehmann; A Chaffotte; S Pochet; G Labesse
Journal:  Protein Sci       Date:  2001-06       Impact factor: 6.725

8.  Genotypic determination of Mycobacterium tuberculosis antibiotic resistance using a novel mutation detection method, the branch migration inhibition M. tuberculosis antibiotic resistance test.

Authors:  Y P Liu; M A Behr; P M Small; N Kurn
Journal:  J Clin Microbiol       Date:  2000-10       Impact factor: 5.948

9.  Effects of overexpression of the alkyl hydroperoxide reductase AhpC on the virulence and isoniazid resistance of Mycobacterium tuberculosis.

Authors:  B Heym; E Stavropoulos; N Honoré; P Domenech; B Saint-Joanis; T M Wilson; D M Collins; M J Colston; S T Cole
Journal:  Infect Immun       Date:  1997-04       Impact factor: 3.441

10.  Mycobacterium species identification and rifampin resistance testing with high-density DNA probe arrays.

Authors:  A Troesch; H Nguyen; C G Miyada; S Desvarenne; T R Gingeras; P M Kaplan; P Cros; C Mabilat
Journal:  J Clin Microbiol       Date:  1999-01       Impact factor: 5.948
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