Literature DB >> 7849739

Sex determination.

J R Hawkins1.   

Abstract

The cloning of the 'testis determining gene', SRY, promised a revolution in the understanding of sex determination in humans. The failure to isolate further genes involved in sex determination has been a disappointment. The biology of SRY, however, has kept the field exciting. The discoveries of sex reversing SRY mutations with variable penetrance, but with full expressivity, rapid SRY sequence evolution and circular Sry transcripts could not have been predicted.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 7849739     DOI： 10.1093/hmg/3.suppl_1.1463

Source DB:  PubMed          Journal:  Hum Mol Genet        ISSN： 0964-6906            Impact factor:   6.150


  7 in total

1.  Incomplete masculinisation of XX subjects carrying the SRY gene on an inactive X chromosome.

Authors:  K Kusz; M Kotecki; A Wojda; M Szarras-Czapnik; A Latos-Bielenska; A Warenik-Szymankiewicz; A Ruszczynska-Wolska; J Jaruzelska
Journal:  J Med Genet       Date:  1999-06       Impact factor: 6.318

2.  Neutral evolution of the sex-determining gene transformer in Drosophila.

Authors:  B F McAllister; G A McVean
Journal:  Genetics       Date:  2000-04       Impact factor: 4.562

Review 3.  The molecular genetics of human sex determination.

Authors:  U Wolf
Journal:  J Mol Med (Berl)       Date:  1995-07       Impact factor: 4.599

4.  Rapid sex determination using PCR technique compared to classic cytogenetics.

Authors:  Ahmad Settin; Ezzat Elsobky; Ayman Hammad; Abeer Al-Erany
Journal:  Int J Health Sci (Qassim)       Date:  2008-01

5.  Genetic mapping of the autosomal region involved in XX sex-reversal and horn development in goats.

Authors:  D Vaiman; O Koutita; A Oustry; J M Elsen; E Manfredi; M Fellous; E P Cribiu
Journal:  Mamm Genome       Date:  1996-02       Impact factor: 2.957

6.  Defective importin beta recognition and nuclear import of the sex-determining factor SRY are associated with XY sex-reversing mutations.

Authors:  Vincent R Harley; Sharon Layfield; Claire L Mitchell; Jade K Forwood; Anna P John; Lyndall J Briggs; Sharon G McDowall; David A Jans
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-22       Impact factor: 11.205

7.  Mutations in SOX9, the gene responsible for Campomelic dysplasia and autosomal sex reversal.

Authors:  C Kwok; P A Weller; S Guioli; J W Foster; S Mansour; O Zuffardi; H H Punnett; M A Dominguez-Steglich; J D Brook; I D Young
Journal:  Am J Hum Genet       Date:  1995-11       Impact factor: 11.025
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.