Literature DB >> 7848895

Endothelin and myocardial ischemia.

D Hasdai1, R Kornowski, A Battler.   

Abstract

Endothelin is a potent vasoconstrictor with a wide range of effects on the heart. Changes in myocardial and circulating levels of endothelin have been described in various experimental models of myocardial ischemia, and in humans with acute myocardial infarction and different forms of angina pectoris. The role played by endothelin in the different states of myocardial ischemia is unclear. However, myocardial damage has been shown to be reduced in several experimental models of myocardial infarction by administering agents that block the action of endothelin. The aim of this review article is to present the current literature concerning the interaction between endothelin and the various forms of myocardial ischemia, and to explore the significance of such interactions.

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Year:  1994        PMID： 7848895     DOI： 10.1007/bf00877413

Source DB:  PubMed          Journal:  Cardiovasc Drugs Ther        ISSN： 0920-3206            Impact factor:   3.727


  109 in total

1.  Endothelin-1 stimulates hypertrophy and contractility of neonatal rat cardiac myocytes in a serum-free medium. II.

Authors:  T Suzuki; H Hoshi; H Sasaki; Y Mitsui
Journal:  J Cardiovasc Pharmacol       Date:  1991       Impact factor: 3.105

2.  Identification of cardiac endothelin binding sites in rats: downregulation of left atrial endothelin binding sites in response to myocardial infarction.

Authors:  P Nambi; M Pullen; J W Egan; E F Smith
Journal:  Pharmacology       Date:  1991       Impact factor: 2.547

3.  Inducible endothelin mRNA expression and peptide secretion in cultured human vascular smooth muscle cells.

Authors:  T J Resink; A W Hahn; T Scott-Burden; J Powell; E Weber; F R Bühler
Journal:  Biochem Biophys Res Commun       Date:  1990-05-16       Impact factor: 3.575

4.  Endothelin has potent direct inotropic and chronotropic effects in cultured heart cells.

Authors:  V Concas; S Laurent; A M Brisac; C Perret; M Safar
Journal:  J Hypertens Suppl       Date:  1989-12

5.  Endothelin-1 inhibits platelet aggregation in vivo: a study with 111indium-labelled platelets.

Authors:  C Thiemermann; G R May; C P Page; J R Vane
Journal:  Br J Pharmacol       Date:  1990-02       Impact factor: 8.739

6.  Characterization of positive inotropic effect of endothelin on mammalian ventricular myocardium.

Authors:  M Takanashi; M Endoh
Journal:  Am J Physiol       Date:  1991-09

7.  Myocardial contractile actions of endothelin-1 in rat and rabbit papillary muscles. Role of endocardial endothelium.

Authors:  K Li; D J Stewart; J L Rouleau
Journal:  Circ Res       Date:  1991-08       Impact factor: 17.367

8.  Contribution of endogenous endothelin to the extension of myocardial infarct size in rats.

Authors:  T Watanabe; N Suzuki; N Shimamoto; M Fujino; A Imada
Journal:  Circ Res       Date:  1991-08       Impact factor: 17.367

9.  Influence of endothelin on human coronary arteries and localization of its binding sites.

Authors:  A H Chester; M R Dashwood; J G Clarke; S W Larkin; G J Davies; S Tadjkarimi; A Maseri; M H Yacoub
Journal:  Am J Cardiol       Date:  1989-06-01       Impact factor: 2.778

10.  Endothelins, peptides with potent vasoactive properties, are produced by human macrophages.

Authors:  H Ehrenreich; R W Anderson; C H Fox; P Rieckmann; G S Hoffman; W D Travis; J E Coligan; J H Kehrl; A S Fauci
Journal:  J Exp Med       Date:  1990-12-01       Impact factor: 14.307
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  6 in total

1.  Analysis of inositol phosphates in heart tissue using anion-exchange high-performance liquid chromatography.

Authors:  E A Woodcock
Journal:  Mol Cell Biochem       Date:  1997-07       Impact factor: 3.396

Review 2.  [Angina pectoris in extracoronary diseases].

Authors:  A Wilke; B Noll; B Maisch
Journal:  Herz       Date:  1999-04       Impact factor: 1.443

Review 3.  Calcium antagonists in myocardial ischemia/reperfusion--update 2012.

Authors:  Petra Kleinbongard; Theodor Baars; Gerd Heusch
Journal:  Wien Med Wochenschr       Date:  2012-06-14

4.  Endothelin-1-induced reduction of myocardial infarct size by activation of ATP-sensitive potassium channels in a rabbit model of myocardial ischaemia and reperfusion.

Authors:  E J Hide; J Piper; C Thiemermann
Journal:  Br J Pharmacol       Date:  1995-11       Impact factor: 8.739

5.  Oxidative Stress and Microcirculatory Flow Abnormalities in the Ventricles during Atrial Fibrillation.

Authors:  Andreas Goette; Alicja Bukowska; Christopher H Lillig; Uwe Lendeckel
Journal:  Front Physiol       Date:  2012-07-05       Impact factor: 4.566

6.  Circulating levels of endothelin-1 in a homogenous Gulf Arab population with untreated essential hypertension.

Authors:  Enyioma Obineche; Abdishakur M Abdulle; Awais M Bokhari; Javed Y Yasin; Michael P T Gillett
Journal:  Ann Saudi Med       Date:  2006 Sep-Oct       Impact factor: 1.526
  6 in total

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