Literature DB >> 7847871

Proton magnetic resonance spectroscopic imaging in patients with frontal lobe epilepsy.

P A Garcia1, K D Laxer, J van der Grond, J W Hugg, G B Matson, M W Weiner.   

Abstract

Proton magnetic resonance spectroscopic imaging (1H MRSI) has demonstrated decreased N-acetyl compounds (NA) in the epileptogenic hippocampus in patients with temporal lobe epilepsy. We studied 8 patients with frontal lobe epilepsy and found mean NA/creatine (Cr) in the epileptogenic frontal lobe decreased by 27% compared with that of the contralateral homologous region (1.81 +/- 0.36 vs 2.49 +/- 0.60, p < 0.008). In every patient, NA/Cr was decreased in the epileptogenic region by at least 5%. These findings suggest that 1H MRSI may be useful in the presurgical evaluation of patients with frontal lobe epilepsy.

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Year:  1995        PMID： 7847871     DOI： 10.1002/ana.410370222

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  7 in total

1.  Temporal lobe epilepsy: bilateral hippocampal metabolite changes revealed at proton MR spectroscopic imaging.

Authors:  G R Ende; K D Laxer; R C Knowlton; G B Matson; N Schuff; G Fein; M W Weiner
Journal:  Radiology       Date:  1997-03       Impact factor: 11.105

2.  Metabolite phantom correction of the nonuniform volume-selection profiles in MR spectroscopic imaging: application to temporal lobe epilepsy.

Authors:  J O Jesper Lundbom; Kim E Vuori; Eija K Gaily; R I Marja-Liisa Granström; Göran C Blomstedt; Anna-Maija Häkkinen; Sami M Heikkinen; Nina M I Lundbom
Journal:  AJNR Am J Neuroradiol       Date:  2005-05       Impact factor: 3.825

3.  Identification of the epileptogenic lobe in neocortical epilepsy with proton MR spectroscopic imaging.

Authors:  Susanne G Mueller; Kenneth D Laxer; Jerome A Barakos; Nathan Cashdollar; Derek L Flenniken; Peter Vermathen; Gerald B Matson; Michael W Weiner
Journal:  Epilepsia       Date:  2004-12       Impact factor: 5.864

Review 4.  Advances in neuroimaging: management of partial epileptic syndromes.

Authors:  Barbara Schäuble; Gregory D Cascino
Journal:  Neurosurg Rev       Date:  2003-08-22       Impact factor: 3.042

Review 5.  [(1)H MR spectroscopy. Methods and applications in diagnosis and assessment of surgical and conservative treatment strategies in epilepsies].

Authors:  T Hammen; H Stefan
Journal:  Nervenarzt       Date:  2004-10       Impact factor: 1.214

Review 6.  1H MR spectroscopy in patients with mesial temporal epilepsy.

Authors:  M Hájek; M Dezortová; V Komárek
Journal:  MAGMA       Date:  1998-12       Impact factor: 2.310

7.  (1)H MR spectroscopic imaging in patients with MRI-negative extratemporal epilepsy: correlation with ictal onset zone and histopathology.

Authors:  Pavel Krsek; Milan Hajek; Monika Dezortova; Filip Jiru; Antonin Skoch; Petr Marusic; Josef Zamecnik; Martin Kyncl; Michal Tichy; Vladimir Komarek
Journal:  Eur Radiol       Date:  2007-03-06       Impact factor: 7.034
  7 in total

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