Literature DB >> 7846284

Brain choline in depression: in vivo detection of potential pharmacodynamic effects of antidepressant therapy using hydrogen localized spectroscopy.

H C Charles1, F Lazeyras, K R Krishnan, O B Boyko, M Payne, D Moore.   

Abstract

1. Seven subjects with depression and matched controls were studied using proton spectroscopy to test the hypothesis that choline will be elevated in depression. 2. The proton spectroscopy was repeated after recovery from depression. 3. The study confirmed a state dependent increase in choline in the brain. 4. This change may be used as an in vivo marker of change in depression.

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Year:  1994        PMID： 7846284     DOI： 10.1016/0278-5846(94)90115-5

Source DB:  PubMed          Journal:  Prog Neuropsychopharmacol Biol Psychiatry        ISSN： 0278-5846            Impact factor:   5.067


  28 in total

1.  Region and tissue differences of metabolites in normally aged brain using multislice 1H magnetic resonance spectroscopic imaging.

Authors:  N Schuff; F Ezekiel; A C Gamst; D L Amend; A A Capizzano; A A Maudsley; M W Weiner
Journal:  Magn Reson Med       Date:  2001-05       Impact factor: 4.668

Review 2.  Research applications of magnetic resonance spectroscopy to investigate psychiatric disorders.

Authors:  Stephen R Dager; Neva M Corrigan; Todd L Richards; Stefan Posse
Journal:  Top Magn Reson Imaging       Date:  2008-04

Review 3.  Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system.

Authors:  Antoine Taly; Pierre-Jean Corringer; Denis Guedin; Pierre Lestage; Jean-Pierre Changeux
Journal:  Nat Rev Drug Discov       Date:  2009-09       Impact factor: 84.694

Review 4.  Imaging Biomarkers of the Neuroimmune System among Substance Use Disorders: A Systematic Review.

Authors:  Eric A Woodcock; Ansel T Hillmer; Graeme F Mason; Kelly P Cosgrove
Journal:  Mol Neuropsychiatry       Date:  2019-05-09

Review 5.  The catecholaminergic-cholinergic balance hypothesis of bipolar disorder revisited.

Authors:  Jordy van Enkhuizen; David S Janowsky; Berend Olivier; Arpi Minassian; William Perry; Jared W Young; Mark A Geyer
Journal:  Eur J Pharmacol       Date:  2014-08-05       Impact factor: 4.432

6.  Subcortical and medial temporal MR-detectable metabolite abnormalities in unipolar major depression.

Authors:  Gabriele Ende; Traute Demirakca; Sigrid Walter; Tim Wokrina; Alexander Sartorius; Dirk Wildgruber; Fritz A Henn
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2007-02       Impact factor: 5.270

7.  Lithium does not alter the choline/creatine ratio in the temporal lobe of human volunteers as measured by proton magnetic resonance spectroscopy.

Authors:  P H Silverstone; C C Hanstock; S Rotzinger
Journal:  J Psychiatry Neurosci       Date:  1999-05       Impact factor: 6.186

8.  Biochemical abnormalities of the medial temporal lobe and medial prefrontal cortex in late-life depression.

Authors:  Talaignair N Venkatraman; Ranga R Krishnan; David C Steffens; Allen W Song; Warren D Taylor
Journal:  Psychiatry Res       Date:  2009-04-30       Impact factor: 3.222

9.  The kynurenine pathway in adolescent depression: preliminary findings from a proton MR spectroscopy study.

Authors:  Vilma Gabbay; Leonard Liebes; Yisrael Katz; Songtao Liu; Sandra Mendoza; James S Babb; Rachel G Klein; Oded Gonen
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2009-09-21       Impact factor: 5.067

10.  Anterior cingulate cortex choline levels in female adolescents with unipolar versus bipolar depression: a potential new tool for diagnosis.

Authors:  Xian-Feng Shi; Lauren N Forrest; M Danielle Kuykendall; Andrew P Prescot; Young-Hoon Sung; Rebekah S Huber; Tracy L Hellem; Eun-Kee Jeong; Perry F Renshaw; Douglas G Kondo
Journal:  J Affect Disord       Date:  2014-06-02       Impact factor: 4.839
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