Literature DB >> 7846200

Effect of selective 5-HT1A agonists and 5-HT2 antagonists on inherited catalepsy in rats.

A V Kulikov1, V G Kolpakov, G B Maslova, I Kozintsev, N K Popova.   

Abstract

The effects of the selective 5-HT1A agonists 8-OH-DPAT and flesinoxan and the selective 5-HT2 antagonists ritanserin and ketanserin on immobility time in rats bred for predisposition to catalepsy have been studied. Treatment with 8-OH-DPAT as well as flesinoxan caused a marked dose-dependent decrease in immobility time. Ritanserin and ketanserin did not affect immobility time at any dose tested. It was suggested that 5HT1A rather than 5-HT2 serotonin receptors are involved in the catalepsy and that an hereditary predisposition to catalepsy may be the result of an inherited alteration in 5-HT1A receptors.

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Year:  1994        PMID： 7846200     DOI： 10.1007/bf02245460

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  12 in total

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Authors:  J Maj; E Mogilnicka; B Przewlocka
Journal:  Pharmacol Biochem Behav       Date:  1975 Jan-Feb       Impact factor: 3.533

2.  The effect of serotonergic agents on haloperidol-induced catalepsy.

Authors:  P B Hicks
Journal:  Life Sci       Date:  1990       Impact factor: 5.037

3.  Effect of the 5-HT1A receptor agonist 8-OH-DPAT on the release of 5-HT in dorsal and median raphe-innervated rat brain regions as measured by in vivo microdialysis.

Authors:  S Hjorth; T Sharp
Journal:  Life Sci       Date:  1991       Impact factor: 5.037

4.  8-Hydroxy-2-(di-n-propylamino) tetralin, a selective serotonin1A receptor agonist, blocks haloperidol-induced catalepsy by an action on raphe nuclei medianus and dorsalis.

Authors:  R W Invernizzi; L Cervo; R Samanin
Journal:  Neuropharmacology       Date:  1988-05       Impact factor: 5.250

Review 5.  Functional correlates of serotonin 5-HT1 recognition sites.

Authors:  D Hoyer
Journal:  J Recept Res       Date:  1988

Review 6.  5-Hydroxytryptamine receptor subtypes.

Authors:  S J Peroutka
Journal:  Annu Rev Neurosci       Date:  1988       Impact factor: 12.449

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Authors:  J J Balsara; J H Jadhav; A G Chandorkar
Journal:  Psychopharmacology (Berl)       Date:  1979-03-29       Impact factor: 4.530

8.  Activity of tryptophan hydroxylase in brain of hereditary predisposed to catalepsy rats.

Authors:  A V Kulikov; E Y Kozlachkova; N K Popova
Journal:  Pharmacol Biochem Behav       Date:  1992-12       Impact factor: 3.533

9.  Further studies of the mechanism behind scopolamine-induced reversal of antistereotypic and cataleptogenic effects of neuroleptics in rats.

Authors:  J Arnt; J Hyttel; T Bach-Lauritsen
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1986-10

10.  Effect of metergoline, fenfluramine, and 8-OHDPAT on catalepsy induced by haloperidol or morphine.

Authors:  C L Broekkamp; S K Oosterloo; H H Berendsen; A M van Delft
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1988-08       Impact factor: 3.000
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  5 in total

1.  The mapping of the gene of susceptibility to catalepsy in mice using polymorphic microsatellite markers.

Authors:  A V Kulikov; D V Bazovkina; M P Moisan; P Mormede
Journal:  Dokl Biol Sci       Date:  2003 Nov-Dec

Review 2.  Mechanisms of action of atypical antipsychotic drugs: a critical analysis.

Authors:  B J Kinon; J A Lieberman
Journal:  Psychopharmacology (Berl)       Date:  1996-03       Impact factor: 4.530

3.  A new synthetic varacin analogue, 8-(trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine hydrochloride (TC-2153), decreased hereditary catalepsy and increased the BDNF gene expression in the hippocampus in mice.

Authors:  Alexander V Kulikov; Maria A Tikhonova; Elizabeth A Kulikova; Konstantin P Volcho; Tatyana M Khomenko; Nariman F Salakhutdinov; Nina K Popova
Journal:  Psychopharmacology (Berl)       Date:  2011-11-30       Impact factor: 4.530

4.  Chronic actions of thyroxine on behavior and serotonin receptors in mouse strains with contrasting predispositions to catalepsy.

Authors:  E A Zubkov; A V Kulikov; V S Naumenko; N K Popova
Journal:  Neurosci Behav Physiol       Date:  2009-10-14

5.  Alterations in pharmacological and behavioural responses in recombinant mouse line with an increased predisposition to catalepsy: role of the 5-HT1A receptor.

Authors:  E A Kulikova; D V Bazovkina; A E Akulov; A S Tsybko; D V Fursenko; A V Kulikov; V S Naumenko; E Ponimaskin; E M Kondaurova
Journal:  Br J Pharmacol       Date:  2016-04-21       Impact factor: 8.739
  5 in total

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