Literature DB >> 7844036

Spectomycins, new antibacterial compounds produced by Streptomyces spectabilis: isolation, structures, and biosynthesis.

A L Staley1, K L Rinehart.   

Abstract

Three new tetrahydroanthracene antibiotics have been isolated from modified culture broths of Streptomyces spectabilis. The new compounds, spectomycins A1, A2 and B1, exist as monomeric (C20H20O7, A1; C19H18O7, A2) and as symmetrical dimeric (C38H34O14; B1) forms. Only spectomycin B1 has moderate activity against Gram-positive microorganisms. We report here the structure elucidation and biosynthetic origin of these compounds.

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Year:  1994        PMID： 7844036     DOI： 10.7164/antibiotics.47.1425

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  3 in total

1.  Hangtaimycin, a peptide secondary metabolite discovered from Streptomyces spectabilis CPCC 200148 by chemical screening.

Authors:  Lijie Zuo; Bingya Jiang; Zhibo Jiang; Wei Zhao; Shufen Li; Hongyu Liu; Bin Hong; Liyan Yu; Limin Zuo; Linzhuan Wu
Journal:  J Antibiot (Tokyo)       Date:  2016-03-09       Impact factor: 2.649

2.  Novel aromatic polyketides from soil Streptomyces spp.: purification, characterization and bioactivity studies.

Authors:  Sunita Bundale; Deovrat Begde; Dhanashree Pillai; Karishma Gangwani; Nandita Nashikkar; Tukaram Kadam; Avinash Upadhyay
Journal:  World J Microbiol Biotechnol       Date:  2018-04-24       Impact factor: 3.312

Review 3.  Current Status of SUMOylation Inhibitors.

Authors:  Christopher M Brackett; Brian S J Blagg
Journal:  Curr Med Chem       Date:  2021       Impact factor: 4.530
  3 in total

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