UNLABELLED: In three children with chronic liver disease of different aetiology without obvious hepatic encephalopathy, bilateral and symmetrical hyperintensity of the globus pallidus in T1-weighted images was found on cranial MRI. Reversibility was shown in one child with autoimmune hepatitis after normalisation of liver function tests under immunosuppressive therapy. CONCLUSION: As central nervous system involvement in liver disease is only partially understood, brain imaging by MRI offers a potential additional tool to further elucidate the incidence and time course of previously undetected brain alterations.
UNLABELLED: In three children with chronic liver disease of different aetiology without obvious hepatic encephalopathy, bilateral and symmetrical hyperintensity of the globus pallidus in T1-weighted images was found on cranial MRI. Reversibility was shown in one child with autoimmune hepatitis after normalisation of liver function tests under immunosuppressive therapy. CONCLUSION: As central nervous system involvement in liver disease is only partially understood, brain imaging by MRI offers a potential additional tool to further elucidate the incidence and time course of previously undetected brain alterations.
Authors: A Pujol; J Pujol; F Graus; A Rimola; J Peri; J M Mercader; J C García-Pagan; J Bosch; J Rodés; E Tolosa Journal: Neurology Date: 1993-01 Impact factor: 9.910
Authors: E Genovese; M Maghnie; G Maggiore; C Tinelli; F Lizzoli; C De Giacomo; S Pozza; R Campani Journal: AJNR Am J Neuroradiol Date: 2000-05 Impact factor: 4.966