Literature DB >> 7838006

The free radical flux theory of sleep.

E Reimund1.   

Abstract

A theory of sleep is proposed in which cerebral free radicals accumulate during wakefulness and are removed during sleep. Removal of excess free radicals during sleep is accomplished by decreased rate of formation of free radicals, and increased efficiency of endogenous antioxidant mechanisms. Thus, sleep functions essentially as an antioxidant for the brain.

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Year:  1994        PMID： 7838006     DOI： 10.1016/0306-9877(94)90071-x

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN： 0306-9877            Impact factor:   1.538


  51 in total

1.  A quantitative, theoretical framework for understanding mammalian sleep.

Authors:  Van M Savage; Geoffrey B West
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-10       Impact factor: 11.205

Review 2.  The neurophysiological basis of excessive daytime sleepiness: suggestions of an altered state of consciousness.

Authors:  P K Hitchcott; D Menicucci; S Frumento; A Zaccaro; A Gemignani
Journal:  Sleep Breath       Date:  2019-05-28       Impact factor: 2.816

Review 3.  The UPR and the anti-oxidant response: relevance to sleep and sleep loss.

Authors:  Marishka K Brown; Nirinjini Naidoo
Journal:  Mol Neurobiol       Date:  2010-03-17       Impact factor: 5.590

4.  Sleep deprivation under sustained hypoxia protects against oxidative stress.

Authors:  Lalini Ramanathan; Jerome M Siegel
Journal:  Free Radic Biol Med       Date:  2011-08-25       Impact factor: 7.376

Review 5.  About sleep's role in memory.

Authors:  Björn Rasch; Jan Born
Journal:  Physiol Rev       Date:  2013-04       Impact factor: 37.312

Review 6.  Oxidative stress, cancer, and sleep deprivation: is there a logical link in this association?

Authors:  Juliana Noguti; Monica Levy Andersen; Chiara Cirelli; Daniel Araki Ribeiro
Journal:  Sleep Breath       Date:  2013-02-01       Impact factor: 2.816

7.  Differential effects of paradoxical sleep deprivation on memory and oxidative stress.

Authors:  Alisson Menezes Araujo Lima; Veralice Meireles Sales de Bruin; Emiliano Ricardo Vasconcelos Rios; Pedro Felipe Carvalhedo de Bruin
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2014-01-15       Impact factor: 3.000

8.  Short-term total sleep deprivation in the rat increases antioxidant responses in multiple brain regions without impairing spontaneous alternation behavior.

Authors:  Lalini Ramanathan; Shuxin Hu; Sally A Frautschy; Jerome M Siegel
Journal:  Behav Brain Res       Date:  2009-10-20       Impact factor: 3.332

9.  Morning impairment in vascular function is unrelated to overnight sleep or the inactivity that accompanies sleep.

Authors:  Saurabh S Thosar; Alec M Berman; Maya X Herzig; Sally A Roberts; Michael R Lasarev; Steven A Shea
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2018-08-08       Impact factor: 3.619

Review 10.  Sleep and the single neuron: the role of global slow oscillations in individual cell rest.

Authors:  Vladyslav V Vyazovskiy; Kenneth D Harris
Journal:  Nat Rev Neurosci       Date:  2013-05-02       Impact factor: 34.870
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