| Literature DB >> 7837995 |
K O'Hara1.
Abstract
A new method of measuring the activity of macrolide antibiotic esterase in whole bacteria and in crude enzyme extracts was determined through the application of nuclear magnetic resonance spectrometry. The structure of the enzymatically esterolytic cleavage compound of oleandomycin was clearly shown to be the cyclic hemiacetal between the C-9 keto and the hydroxy group of C-13 in the open macrolide nucleus by physicochemical techniques.Entities:
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Year: 1994 PMID： 7837995
Source DB: PubMed Journal: Microbios ISSN： 0026-2633