Literature DB >> 7837220

Anti-human immunodeficiency virus and anti-hepatitis-B virus activities and toxicities of the enantiomers of 2'-deoxy-3'-oxa-4'-thiocytidine and their 5-fluoro analogues in vitro.

T S Mansour1, H Jin, W Wang, E U Hooker, C Ashman, N Cammack, H Salomon, A R Belmonte, M A Wainberg.   

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Year:  1995        PMID: 7837220     DOI: 10.1021/jm00001a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  11 in total

1.  Antiviral activity of 2'-deoxy-3'-oxa-4'-thiocytidine (BCH-10652) against lamivudine-resistant human immunodeficiency virus type 1 in SCID-hu Thy/Liv mice.

Authors:  C A Stoddart; M E Moreno; V D Linquist-Stepps; C Bare; M R Bogan; A Gobbi; R W Buckheit; J Bedard; R F Rando; J M McCune
Journal:  Antimicrob Agents Chemother       Date:  2000-03       Impact factor: 5.191

2.  Anti-human immunodeficiency virus type 1 activity, intracellular metabolism, and pharmacokinetic evaluation of 2'-deoxy-3'-oxa-4'-thiocytidine.

Authors:  J M de Muys; H Gourdeau; N Nguyen-Ba; D L Taylor; P S Ahmed; T Mansour; C Locas; N Richard; M A Wainberg; R F Rando
Journal:  Antimicrob Agents Chemother       Date:  1999-08       Impact factor: 5.191

3.  In vitro antiretroviral activity and in vitro toxicity profile of SPD754, a new deoxycytidine nucleoside reverse transcriptase inhibitor for treatment of human immunodeficiency virus infection.

Authors:  Z Gu; B Allard; J M de Muys; J Lippens; R F Rando; N Nguyen-Ba; C Ren; P McKenna; D L Taylor; R C Bethell
Journal:  Antimicrob Agents Chemother       Date:  2006-02       Impact factor: 5.191

4.  Selection and characterization of human immunodeficiency virus type 1 variants resistant to the (+) and (-) enantiomers of 2'-deoxy-3'-oxa-4'-thio-5-fluorocytidine.

Authors:  N Richard; H Salomon; R Rando; T Mansour; T L Bowlin; M A Wainberg
Journal:  Antimicrob Agents Chemother       Date:  2000-05       Impact factor: 5.191

5.  Safety, pharmacokinetics, and efficacy of (+/-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine with efavirenz and stavudine in antiretroviral-naïve human immunodeficiency virus-infected patients.

Authors:  C Herzmann; K Arastèh; R L Murphy; H Schulbin; P Kreckel; D Drauz; R F Schinazi; A Beard; L Cartee; M J Otto
Journal:  Antimicrob Agents Chemother       Date:  2005-07       Impact factor: 5.191

6.  Anti-human immunodeficiency virus activities of nucleosides and nucleotides: correlation with molecular electrostatic potential data.

Authors:  T Mickle; V Nair
Journal:  Antimicrob Agents Chemother       Date:  2000-11       Impact factor: 5.191

7.  Diminished RNA primer usage associated with the L74V and M184V mutations in the reverse transcriptase of human immunodeficiency virus type 1 provides a possible mechanism for diminished viral replication capacity.

Authors:  Karidia Diallo; Bruno Marchand; Xin Wei; Luciano Cellai; Matthias Götte; Mark A Wainberg
Journal:  J Virol       Date:  2003-08       Impact factor: 5.103

8.  Antiviral nucleoside analogs.

Authors:  Vladimir E Kataev; Bulat F Garifullin
Journal:  Chem Heterocycl Compd (N Y)       Date:  2021-05-14       Impact factor: 1.277

9.  Lamivudine therapy for korean children with chronic hepatitis B.

Authors:  Hong Koh; Seoung Yon Baek; Ki Sup Chung
Journal:  Yonsei Med J       Date:  2007-12-31       Impact factor: 2.759

10.  Synergistic activity of troxacitabine (Troxatyl) and gemcitabine in pancreatic cancer.

Authors:  Vijaya L Damaraju; David Y Bouffard; Clarence K W Wong; Marilyn L Clarke; John R Mackey; Lorraine Leblond; Carol E Cass; Mike Grey; Henriette Gourdeau
Journal:  BMC Cancer       Date:  2007-07-03       Impact factor: 4.430

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