OBJECTIVE: To assess the risk of fractures among patients with ankylosing spondylitis (AS). METHODS: A population based cohort study compared fracture incidence in an inception cohort of 158 Rochester, Minnesota residents newly diagnosed with AS between 1935 and 1989 with expected rates from the same community. RESULTS: In 2,398 person-years of observation, there was no increase in the risk of limb fractures, but there was a pronounced increase in the risk of thoracolumbar compression fractures (standardized morbidity ratio = 7.6; 95% CI, 4.3-12.6) among those with AS. CONCLUSION: These data point to the importance of measures aimed at maintaining axial skeletal status in patients with AS.
OBJECTIVE: To assess the risk of fractures among patients with ankylosing spondylitis (AS). METHODS: A population based cohort study compared fracture incidence in an inception cohort of 158 Rochester, Minnesota residents newly diagnosed with AS between 1935 and 1989 with expected rates from the same community. RESULTS: In 2,398 person-years of observation, there was no increase in the risk of limb fractures, but there was a pronounced increase in the risk of thoracolumbar compression fractures (standardized morbidity ratio = 7.6; 95% CI, 4.3-12.6) among those with AS. CONCLUSION: These data point to the importance of measures aimed at maintaining axial skeletal status in patients with AS.
Authors: Percival D Sampaio-Barros; Silvana Filardi; Adil Muhib Samara; João Francisco Marques-Neto Journal: Clin Rheumatol Date: 2004-07-16 Impact factor: 2.980
Authors: Mirjam K de Vries; Anne S van Drumpt; Barend J van Royen; J Christiaan van Denderen; Radu A Manoliu; Irene E van der Horst-Bruinsma Journal: Clin Rheumatol Date: 2010-05-23 Impact factor: 2.980
Authors: Johannes L Bron; Mirjam K de Vries; Marieke N Snieders; Irene E van der Horst-Bruinsma; Barend J van Royen Journal: Clin Rheumatol Date: 2009-03-18 Impact factor: 2.980