Literature DB >> 7837

Calcium-independent modulation of cyclic GMP and activation of guanylate cyclase by nitrosamines.

F R DeRubertis, P A Craven.   

Abstract

Nitrosamines markedly increase concentrations of guanosine 3', 5' - monophosphate (cyclic GMP) in several tissues from the rat and in human colonic mucosa. These agents are effective in the absence of extracellular calcium and enhance guanylate cyclase activity in tissue homogenates. Stimulation of cyclic GMP was greatest in liver, where the carcinogenic activity of nitrosamines is also most pronounced.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 7837     DOI： 10.1126/science.7837

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  11 in total

1.  Effects of manganese on cyclic GMP levels in the rat ductus deferens.

Authors:  K D Schultz; K Schultz; G Schultz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-07       Impact factor: 3.000

2.  Nicotine decreases guanylate cyclase activity.

Authors:  D L Vesely; G S Levey
Journal:  Bull Environ Contam Toxicol       Date:  1978-07       Impact factor: 2.151

3.  Soluble bovine adrenal cortex guanylate cyclase: effect of sodium nitroprusside, nitrosamines, and hydrophobic ligands on activity, substrate specificity and cation requirement.

Authors:  C J Struck; H Glossmann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-08       Impact factor: 3.000

4.  Inhibition of growth and guanylate cyclase activity of an undifferentiated prostate adenocarcinoma by an extract of the balsam pear (Momordica charantia abbreviata).

Authors:  A J Claflin; D L Vesely; J L Hudson; C B Bagwell; D C Lehotay; T M Lo; M A Fletcher; N L Block; G S Levey
Journal:  Proc Natl Acad Sci U S A       Date:  1978-02       Impact factor: 11.205

5.  Activation of guanylate cyclase by superoxide dismutase and hydroxyl radical: a physiological regulator of guanosine 3',5'-monophosphate formation.

Authors:  C K Mittal; F Murad
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205

6.  Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations.

Authors:  W P Arnold; C K Mittal; S Katsuki; F Murad
Journal:  Proc Natl Acad Sci U S A       Date:  1977-08       Impact factor: 11.205

Review 7.  Cyclic guanosine monophosphate as a mediator of vasodilation.

Authors:  F Murad
Journal:  J Clin Invest       Date:  1986-07       Impact factor: 14.808

8.  Changes in mouse skin cyclic nucleotides during chemical carcinogenesis and tumor response to treatment with BCG, L-Dopa and cyclic DBAMP.

Authors:  E Busse; H Rose; K H Riessbeck
Journal:  J Cancer Res Clin Oncol       Date:  1979-06-08       Impact factor: 4.553

9.  Activation of purified soluble guanylate cyclase by protoporphyrin IX.

Authors:  L J Ignarro; K S Wood; M S Wolin
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

10.  Brief periods of nitric oxide inhalation protect against myocardial ischemia-reperfusion injury.

Authors:  Yasuko Nagasaka; Bernadette O Fernandez; Maria F Garcia-Saura; Bodil Petersen; Fumito Ichinose; Kenneth D Bloch; Martin Feelisch; Warren M Zapol
Journal:  Anesthesiology       Date:  2008-10       Impact factor: 7.892
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.