Literature DB >> 7835706

A widely expressed novel C2H2 zinc-finger protein with multiple consensus phosphorylation sites is conserved in mouse and man.

Y Saotome1, C G Winter, D Hirsh.   

Abstract

We have cloned a murine cDNA whose deduced sequence encodes a 455-amino-acid (aa) zinc-finger protein (Zfp), PZf (penta Zf protein). Sequence analysis shows that PZf has multiple phosphorylation consensus sites for casein kinase II and protein kinase C in its N-terminal portion. This region (aa 1 to 197), which does not share significant homology to known aa sequences, has a number of charged (39 Glu, 15 Asp, 23 Lys, 22 Arg) and hydroxyl (20 Ser, 12 Thr) aa. This potentially phosphorylatable region is followed by five C2H2 Zf in the middle of the protein. The Pzf gene is transcribed as a 5-kb mRNA in all murine tissues examined. The human genome also seems to contain one or more Pzf-related genes.

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Year:  1995        PMID： 7835706     DOI： 10.1016/0378-1119(94)00717-7

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  14 in total

1.  Searching interaction partners of protein kinase CK2beta subunit by two-hybrid screening.

Authors:  S Grein; K Raymond; C Cochet; W Pyerin; E M Chambaz; O Filhol
Journal:  Mol Cell Biochem       Date:  1999-01       Impact factor: 3.396

2.  Expression pattern of cellular nucleic acid-binding protein (CNBP) during embryogenesis and spermatogenesis of gibel carp.

Authors:  Jing-Xia Liu; Yan-Hua Zhai; Jian-Fang Gui
Journal:  Mol Biol Rep       Date:  2008-08-29       Impact factor: 2.316

3.  Sox10 regulates ciliary neurotrophic factor gene expression in Schwann cells.

Authors:  Yasuhiro Ito; Stefan Wiese; Natalja Funk; Alexandra Chittka; Wilfried Rossoll; Heike Bömmel; Kazuhiko Watabe; Michael Wegner; Michael Sendtner
Journal:  Proc Natl Acad Sci U S A       Date:  2006-05-09       Impact factor: 11.205

4.  Isolation of candidate hybrid sterility 1 genes by cDNA selection in a 1.1 megabase pair region on mouse chromosome 17.

Authors:  Z Trachtulec; M Mnuková-Fajdelová; R M Hamvas; S Gregorová; W E Mayer; H R Lehrach; V Vincek; J Forejt; J Klein
Journal:  Mamm Genome       Date:  1997-05       Impact factor: 2.957

5.  Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1.

Authors:  Wenchao Wu; Geoffrey M Nelson; Raphael Koch; Katherine A Donovan; Radosław P Nowak; Tayla B Heavican-Foral; Ajit J Nirmal; Huiyun Liu; Lei Yang; Jessica Duffy; Foster Powers; Kristen E Stevenson; Marcus Kenneth Jones; Samuel Y Ng; Gongwei Wu; Salvia Jain; Ran Xu; Sam Amaka; Christopher Trevisani; Nicholas L Donaldson; Patrick R Hagner; Laurence de Leval; Philippe Gaulard; Javeed Iqbal; Anjan Thakurta; Eric S Fischer; Karen Adelman; David M Weinstock
Journal:  Blood       Date:  2022-03-31       Impact factor: 25.476

6.  A role for ciliary neurotrophic factor as an inducer of reactive gliosis, the glial response to central nervous system injury.

Authors:  C G Winter; Y Saotome; S W Levison; D Hirsh
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-20       Impact factor: 11.205

7.  Zinc finger protein 91 positively regulates the production of IL-1β in macrophages by activation of MAPKs and non-canonical caspase-8 inflammasome.

Authors:  Chunliu Mi; Zhe Wang; Ming Yue Li; Zhi Hong Zhang; Juan Ma; Xuejun Jin
Journal:  Br J Pharmacol       Date:  2018-10-15       Impact factor: 8.739

8.  ZFP91: A Noncanonical NF-κB Signaling Pathway Regulator with Oncogenic Properties Is Overexpressed in Prostate Cancer.

Authors:  Lukasz Paschke; Karol Jopek; Marta Szyszka; Marianna Tyczewska; Agnieszka Ziolkowska; Marcin Rucinski; Ludwik K Malendowicz
Journal:  Biomed Res Int       Date:  2016-11-16       Impact factor: 3.411

9.  ZFP91-a newly described gene potentially involved in prostate pathology.

Authors:  Lukasz Paschke; Marcin Rucinski; Agnieszka Ziolkowska; Tomasz Zemleduch; Witold Malendowicz; Zbigniew Kwias; Ludwik K Malendowicz
Journal:  Pathol Oncol Res       Date:  2013-11-23       Impact factor: 3.201

10.  Zinc finger protein 91 (ZFP91) activates HIF-1α via NF-κB/p65 to promote proliferation and tumorigenesis of colon cancer.

Authors:  Juan Ma; Chunliu Mi; Ke Si Wang; Jung Joon Lee; Xuejun Jin
Journal:  Oncotarget       Date:  2016-06-14
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