Literature DB >> 7834351

Expression of a novel non-angiotensin II [125I]CGP 42112 binding site in healing wounds of the rat brain.

M Viswanathan1, A M de Oliveira, F M Correa, J M Saavedra.   

Abstract

We characterized a novel non-angiotensin II binding site that is recognized by the angiotensin II AT2 receptor ligand [125I]CGP 42112, in healing brain wounds of adult rats. The binding, which was highest at 3 days after injury, appears to be localized to activated microglia surrounding the wound. The novel CGP 42112 binding site may have a role in the function of microglia and in mechanisms of tissue repair in the brain.

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Year:  1994        PMID： 7834351     DOI： 10.1016/s0006-8993(09)90035-x

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  3 in total

Review 1.  The discovery of a novel macrophage binding site.

Authors:  Juan M Saavedra; Jaroslav Pavel
Journal:  Cell Mol Neurobiol       Date:  2006-04-22       Impact factor: 5.046

Review 2.  Angiotensin II AT2 Receptors Contribute to Regulate the Sympathoadrenal and Hormonal Reaction to Stress Stimuli.

Authors:  J M Saavedra; I Armando
Journal:  Cell Mol Neurobiol       Date:  2017-09-07       Impact factor: 5.046

3.  The deleterious role of the prostaglandin E2 EP3 receptor in angiotensin II hypertension.

Authors:  Timothy D Bryson; Teja S Pandrangi; Safa Z Khan; Jiang Xu; Tengis S Pavlov; Pablo A Ortiz; Edward Peterson; Pamela Harding
Journal:  Am J Physiol Heart Circ Physiol       Date:  2020-03-06       Impact factor: 4.733
  3 in total

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