Literature DB >> 7833051

Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection.

J Hülsken1, J Behrens, W Birchmeier.   

Abstract

Various structural components of intercellular junctions have recently been found to represent (or be related to) products of tumor-suppressor genes. The tumor-suppressor gene product adenomatous polyposis coli (APC) binds to beta 2-catenin (homologous to the product of Drosophila armadillo), which is cytoplasmically associated with the cell adhesion molecule E-cadherin.

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Year:  1994        PMID: 7833051     DOI: 10.1016/0955-0674(94)90098-1

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN: 0955-0674            Impact factor:   8.382


  28 in total

1.  Explaining differences in the severity of familial adenomatous polyposis and the search for modifier genes.

Authors:  R Houlston; M Crabtree; R Phillips; M Crabtree; I Tomlinson
Journal:  Gut       Date:  2001-01       Impact factor: 23.059

2.  Allele loss, replication errors and loss of expression of E-cadherin in colorectal cancers.

Authors:  M Ilyas; I P Tomlinson; A Hanby; I C Talbot; W F Bodmer
Journal:  Gut       Date:  1997-05       Impact factor: 23.059

3.  Wingless signaling modulates cadherin-mediated cell adhesion in Drosophila imaginal disc cells.

Authors:  Andreas Wodarz; Daniel B Stewart; W James Nelson; Roel Nusse
Journal:  J Cell Sci       Date:  2006-05-23       Impact factor: 5.285

4.  Nonmalignant epithelial cells, potentially invasive in human endometriosis, lack the tumor suppressor molecule E-cadherin.

Authors:  R Gaetje; S Kotzian; G Herrmann; R Baumann; A Starzinski-Powitz
Journal:  Am J Pathol       Date:  1997-02       Impact factor: 4.307

5.  Inhibition of cultured cell growth by vascular endothelial cadherin (cadherin-5/VE-cadherin).

Authors:  L Caveda; I Martin-Padura; P Navarro; F Breviario; M Corada; D Gulino; M G Lampugnani; E Dejana
Journal:  J Clin Invest       Date:  1996-08-15       Impact factor: 14.808

Review 6.  Endothelial adherens junctions: implications in the control of vascular permeability and angiogenesis.

Authors:  E Dejana
Journal:  J Clin Invest       Date:  1996-11-01       Impact factor: 14.808

Review 7.  The cellular basis of metastasis.

Authors:  P Ruiz; U Günthert
Journal:  World J Urol       Date:  1996       Impact factor: 4.226

8.  p120-Catenin is an obligate haploinsufficient tumor suppressor in intestinal neoplasia.

Authors:  Sarah P Short; Jumpei Kondo; Whitney G Smalley-Freed; Haruna Takeda; Michael R Dohn; Anne E Powell; Robert H Carnahan; Mary K Washington; Manish Tripathi; D Michael Payne; Nancy A Jenkins; Neal G Copeland; Robert J Coffey; Albert B Reynolds
Journal:  J Clin Invest       Date:  2017-11-13       Impact factor: 14.808

9.  Anterior axis duplication in Xenopus induced by the over-expression of the cadherin-binding protein plakoglobin.

Authors:  A Karnovsky; M W Klymkowsky
Journal:  Proc Natl Acad Sci U S A       Date:  1995-05-09       Impact factor: 11.205

Review 10.  Adhesion or anti-adhesion in cancer: what matters more?

Authors:  S Jothy; S B Munro; L LeDuy; D McClure; O W Blaschuk
Journal:  Cancer Metastasis Rev       Date:  1995-12       Impact factor: 9.264

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