| Literature DB >> 7832802 |
M Loukovaara1, M Carson, H Adlercreutz.
Abstract
The effect of endogenous estrogens on sex-hormone-binding globulin (SHBG) production was studied in HepG2 cells. 17 beta-estradiol, estrone, and estrogens from both 2- and 16 alpha-hydroxylative pathways stimulated SHBG production, but not in parallel with their binding affinities for the estrogen receptor. Thus, the underlying mechanism may be other than a pure interaction with the estrogen receptor.Entities:
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Year: 1995 PMID: 7832802 DOI: 10.1006/bbrc.1995.1127
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN: 0006-291X Impact factor: 3.575