Literature DB >> 7832802

Regulation of sex-hormone-binding globulin production by endogenous estrogens in vitro.

M Loukovaara1, M Carson, H Adlercreutz.   

Abstract

The effect of endogenous estrogens on sex-hormone-binding globulin (SHBG) production was studied in HepG2 cells. 17 beta-estradiol, estrone, and estrogens from both 2- and 16 alpha-hydroxylative pathways stimulated SHBG production, but not in parallel with their binding affinities for the estrogen receptor. Thus, the underlying mechanism may be other than a pure interaction with the estrogen receptor.

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Year:  1995        PMID: 7832802     DOI: 10.1006/bbrc.1995.1127

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  4 in total

1.  Estrogen responses in killifish (Fundulus heteroclitus) from polluted and unpolluted environments are site- and gene-specific.

Authors:  Sarah R Greytak; Ann M Tarrant; Diane Nacci; Mark E Hahn; Gloria V Callard
Journal:  Aquat Toxicol       Date:  2010-05-19       Impact factor: 4.964

2.  Fat/fiber intakes and sex hormones in healthy premenopausal women in USA.

Authors:  Mylène Aubertin-Leheudre; Sherwood Gorbach; Margo Woods; Johanna T Dwyer; Barry Goldin; Herman Adlercreutz
Journal:  J Steroid Biochem Mol Biol       Date:  2008-08-09       Impact factor: 4.292

3.  Sex hormones, sex hormone binding globulin, and abdominal aortic calcification in women and men in the multi-ethnic study of atherosclerosis (MESA).

Authors:  Erin D Michos; Dhananjay Vaidya; Susan M Gapstur; Pamela J Schreiner; Sherita H Golden; Nathan D Wong; Michael H Criqui; Pamela Ouyang
Journal:  Atherosclerosis       Date:  2008-02-08       Impact factor: 5.162

4.  Characterization of estrogenicity of phytoestrogens in an endometrial-derived experimental model.

Authors:  A C Hopert; A Beyer; K Frank; E Strunck; W Wünsche; G Vollmer
Journal:  Environ Health Perspect       Date:  1998-09       Impact factor: 9.031

  4 in total

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