| Literature DB >> 7832094 |
T Mori1, J Sasaki, H Kawaguchi, K Handa, Y Takada, A Matsunaga, S Kono, K Arakawa.
Abstract
The relation of serum glycoproteins and C-reactive protein (CRP) to severity of coronary atherosclerosis was examined in 133 men and 92 women undergoing coronary angiography. The following serum glycoproteins were determined: alpha 1-antitrypsin, alpha 1-acid glycoprotein, alpha 2-macroglobulin, ceruloplasmin, haptoglobin, fibrinogen, C4b binding protein, and lipoprotein (a) [Lp(a)]. Sex- and age-adjusted levels of alpha 1-antitrypsin, alpha 1-acid glycoproteins, alpha 2-macroglobulin, ceruloplasmin, Lp(a) and CRP were significantly associated with the severity of coronary atherosclerosis as determined by the Gensini score; these associations remained significant even after adjustment for body-mass index, smoking history, hypertension, and total cholesterol, except for Lp(a) (p = 0.075). These findings suggest that certain serum glycoproteins and CRP can serve as independent indicators for the progression of coronary atherosclerosis.Entities:
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Year: 1995 PMID： 7832094 DOI： 10.1016/0002-8703(95)90003-9
Source DB: PubMed Journal: Am Heart J ISSN： 0002-8703 Impact factor: 4.749