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Literature DB >> 7830276

Halicylindramides A-C, antifungal and cytotoxic depsipeptides from the marine sponge Halichondria cylindrata.

Abstract

Halicylindramides A-C (1-3) have been isolated from the Japanese marine sponge Halichondria cylindrata. They are tetradecapeptides with the N-terminus blocked by a formyl group and the C-terminus lactonized with a threonine residue. Their total structures including absolute stereochemistry were determined by a combination of spectral and chemical methods. Halicylindramides A-C were antifungal against Mortierella ramanniana and cytotoxic against P388 murine leukemia cells.

Entities: Chemical Disease Species

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Year: 1995 PMID： 7830276 DOI： 10.1021/jm00002a015

Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446

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Cited

11 in total

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Review 3. Membrane-active peptides from marine organisms--antimicrobials, cell-penetrating peptides and peptide toxins: applications and prospects.

Authors: Nisha Ponnappan; Deepthi Poornima Budagavi; Bhoopesh Kumar Yadav; Archana Chugh
Journal: Probiotics Antimicrob Proteins Date: 2015-03 Impact factor: 4.609

10. Lipophilic fractions from the marine sponge Halichondria sitiens decrease secretion of pro-inflammatory cytokines by dendritic cells and decrease their ability to induce a Th1 type response by allogeneic CD4⁺ T cells.

Authors: Xiaxia Di; Jon T Oskarsson; Sesselja Omarsdottir; Jona Freysdottir; Ingibjorg Hardardottir
Journal: Pharm Biol Date: 2017-12 Impact factor: 3.503

Halicylindramides A-C, antifungal and cytotoxic depsipeptides from the marine sponge Halichondria cylindrata.

Review 1. Natural neo acids and neo alkanes: their analogs and derivatives.

Review 2. Marine natural product peptides with therapeutic potential: Chemistry, biosynthesis, and pharmacology.

Review 3. Membrane-active peptides from marine organisms--antimicrobials, cell-penetrating peptides and peptide toxins: applications and prospects.

Review 4. Marine Cyclic Peptides: Antimicrobial Activity and Synthetic Strategies.

5. Antifungal and Anticancer Activities of a Protein from the Mushroom Cordyceps militaris.

6. Synthesis of complex head-to-side-chain cyclodepsipeptides.

7. Halogenated cyclic peptides isolated from the sponge Corticium sp.

8. Biological activities of ethanolic extracts from deep-sea Antarctic marine sponges.

Review 9. "Head-to-side-chain" cyclodepsipeptides of marine origin.

10. Lipophilic fractions from the marine sponge Halichondria sitiens decrease secretion of pro-inflammatory cytokines by dendritic cells and decrease their ability to induce a Th1 type response by allogeneic CD4⁺ T cells.

Halicylindramides A-C, antifungal and cytotoxic depsipeptides from the marine sponge Halichondria cylindrata.

Review 1. Natural neo acids and neo alkanes: their analogs and derivatives.

Review 2. Marine natural product peptides with therapeutic potential: Chemistry, biosynthesis, and pharmacology.

Review 3. Membrane-active peptides from marine organisms--antimicrobials, cell-penetrating peptides and peptide toxins: applications and prospects.

Review 4. Marine Cyclic Peptides: Antimicrobial Activity and Synthetic Strategies.

5. Antifungal and Anticancer Activities of a Protein from the Mushroom Cordyceps militaris.

6. Synthesis of complex head-to-side-chain cyclodepsipeptides.

7. Halogenated cyclic peptides isolated from the sponge Corticium sp.

8. Biological activities of ethanolic extracts from deep-sea Antarctic marine sponges.

Review 9. "Head-to-side-chain" cyclodepsipeptides of marine origin.

10. Lipophilic fractions from the marine sponge Halichondria sitiens decrease secretion of pro-inflammatory cytokines by dendritic cells and decrease their ability to induce a Th1 type response by allogeneic CD4+ T cells.

10. Lipophilic fractions from the marine sponge Halichondria sitiens decrease secretion of pro-inflammatory cytokines by dendritic cells and decrease their ability to induce a Th1 type response by allogeneic CD4⁺ T cells.