Literature DB >> 7830122

Rapid washout of technetium-99m-MIBI from a large parathyroid adenoma.

F Bénard1, B Lefebvre, F Beuvon, M F Langlois, G Bisson.   

Abstract

We report a case of rapid 99mTc-methoxyisobutylisonitrile (MIBI) clearance from a parathyroid adenoma. A double-phase 99mTc-MIBI parathyroid scintigraphy was performed on a 62-yr-old female evaluated for primary hyperparathyroidism. A large parathyroid adenoma was visualized caudal to the left lobe of the thyroid gland with an unusually rapid washout of the tracer from tumor tissue. Histologic tissue examination confirmed the presence of a parathyroid adenoma and the absence of oxyphil cells. Care should be taken in interpretation of 99mTc-MIBI parathyroid scintigrams because some adenomas can present a rapid release of the radiotracer in a double-phase study. Technetium-99m-MIBI retention could be related to the number of mitochondria-rich cells in parathyroid adenomas or to hyperplasia.

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Year:  1995        PMID： 7830122

Source DB:  PubMed          Journal:  J Nucl Med        ISSN： 0161-5505            Impact factor:   10.057


  14 in total

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Journal:  Endocr Pathol       Date:  2015-09       Impact factor: 3.943

2.  Bilateral retropharyngeal parathyroid hyperplasia detected with 4D multidetector row CT.

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Journal:  AJNR Am J Neuroradiol       Date:  2010-04-22       Impact factor: 3.825

3.  Comparison of hyperparathyroidism types and utility of dual radiopharmaceutical acquisition with Tc99m sestamibi and 123I for localization of rapid washout parathyroid adenomas.

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Journal:  Osteoporos Int       Date:  2019-01-31       Impact factor: 4.507

4.  Preoperative evaluation of parathyroid lesions in patients with concomitant thyroid disease: role of high resolution ultrasonography and dual phase technetium 99m sestamibi scintigraphy.

Authors:  M Kebapci; E Entok; N Kebapci; B Adapinar
Journal:  J Endocrinol Invest       Date:  2004-01       Impact factor: 4.256

5.  Radio-guided parathyroidectomy in patients with primary hyperparathyroidism and concomitant multinodular goiter.

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6.  Primary hyperparathyroidism: imaging to pathology.

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7.  Scintigraphic techniques in primary hyperparathyroidism: from pre-operative localisation to intra-operative imaging.

Authors:  Domenico Rubello; Milton D Gross; Giuliano Mariani; Adil AL-Nahhas
Journal:  Eur J Nucl Med Mol Imaging       Date:  2007-03-10       Impact factor: 10.057

8.  Comparison of Tc-99m pertechnetate images with dual-phase Tc 99m MIBI and SPECT images in primary hyperparathyroidism.

Authors:  Sait Sager; Hojjat Shafipour; Sertac Asa; Sabire Yılmaz; Serkan Teksöz; Cetin Onsel
Journal:  Indian J Endocrinol Metab       Date:  2014-07

9.  A case report of mediastinal ectopic parathyroid adenoma presented as parathyroid crisis localized by SPECT/CT.

Authors:  Weibin Zhou; Min Chen
Journal:  Medicine (Baltimore)       Date:  2016-10       Impact factor: 1.889

10.  Is intraoperative parathyroid hormone monitoring necessary in symptomatic primary hyperparathyroidism with concordant imaging?

Authors:  C Gopalakrishnan Nair; Misha J C Babu; Pradeep Jacob; Riju Menon; Jimmy Mathew
Journal:  Indian J Endocrinol Metab       Date:  2016 Jul-Aug
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