UNLABELLED: The uptake of 2-deoxy-2-[18F]fluoro-D-glucose (FDG) in neck lymph nodes of twelve patients with a squamous-cell carcinoma of the oral cavity was studied with PET in order to detect and locate lymphogenic metastases. METHODS: The results of FDG-PET imaging were compared with clinical, MRI and histopathologic findings. Standardized uptake values (SUV) were also calculated. RESULTS: A sensitivity of 91% and a specificity of 88% were calculated for FDG-PET. In contrast, a sensitivity of 36% and a specificity of 94% were calculated for MRI. Calculated SUVs for reactive lymph nodes, metastatic lymph nodes and the primary tumor were undifferentiated. CONCLUSION: Using FDG-PET, lymph node metastases of squamous-cell carcinomas of the oral cavity can be visualized with a high sensitivity and specificity. FDG-PET can be an improvement in the evaluation of the neck.
UNLABELLED: The uptake of 2-deoxy-2-[18F]fluoro-D-glucose (FDG) in neck lymph nodes of twelve patients with a squamous-cell carcinoma of the oral cavity was studied with PET in order to detect and locate lymphogenic metastases. METHODS: The results of FDG-PET imaging were compared with clinical, MRI and histopathologic findings. Standardized uptake values (SUV) were also calculated. RESULTS: A sensitivity of 91% and a specificity of 88% were calculated for FDG-PET. In contrast, a sensitivity of 36% and a specificity of 94% were calculated for MRI. Calculated SUVs for reactive lymph nodes, metastatic lymph nodes and the primary tumor were undifferentiated. CONCLUSION: Using FDG-PET, lymph node metastases of squamous-cell carcinomas of the oral cavity can be visualized with a high sensitivity and specificity. FDG-PET can be an improvement in the evaluation of the neck.
Authors: Maky A Hafidh; Peter D Lacy; Joe P Hughes; George Duffy; Conrad V Timon Journal: Eur Arch Otorhinolaryngol Date: 2006-05-25 Impact factor: 2.503
Authors: Jolijn Brouwer; Remco de Bree; Emile F I Comans; Jonas A Castelijns; Otto S Hoekstra; C René Leemans Journal: Eur Arch Otorhinolaryngol Date: 2003-12-17 Impact factor: 2.503
Authors: S Dresel; J Grammerstorff; K Schwenzer; K Brinkbäumer; R Schmid; T Pfluger; K Hahn Journal: Eur J Nucl Med Mol Imaging Date: 2003-05-09 Impact factor: 9.236
Authors: Anthony Hannah; Andrew M Scott; Henri Tochon-Danguy; J Gordon Chan; Tim Akhurst; Salvatore Berlangieri; David Price; Gerard J Smith; Tony Schelleman; W J McKay; Andrew Sizeland Journal: Ann Surg Date: 2002-08 Impact factor: 12.969
Authors: S Nagamachi; H Hoshi; S Jinnouchi; T Ohnishi; L G Flores; S Futami; H Nakahara; K Watanabe Journal: Ann Nucl Med Date: 1996-02 Impact factor: 2.668
Authors: Francisco J Civantos; Sandro J Stoeckli; Robert P Takes; Julia A Woolgar; Remco de Bree; Vinidh Paleri; Kenneth O Devaney; Alessandra Rinaldo; Carl E Silver; Vanni Mondin; Jochen A Werner; Alfio Ferlito Journal: Eur Arch Otorhinolaryngol Date: 2010-03-05 Impact factor: 2.503
Authors: R B J de Bondt; P J Nelemans; F Bakers; J W Casselman; C Peutz-Kootstra; B Kremer; P A M Hofman; R G H Beets-Tan Journal: Eur Radiol Date: 2008-10-07 Impact factor: 5.315