Literature DB >> 7829172

Diagnostic and prognostic significance of serum and tissue trace elements in breast malignancy.

K Sharma1, D K Mittal, R C Kesarwani, V P Kamboj.   

Abstract

50 cases of breast malignancy constituted the study group. 26 age and sex matched formed the control group. Serum and tissue trace element viz copper, zinc, selenium and molybdenum levels were estimated by atomic absorption photometry. The study group showed significant hypercupremia and molybdenemia, hypozincaemia and hyposeleniamia. The reversal of trend was documented after therapy. The tissue level of copper and molybdenum was high and zinc and selenium was low. An association between serum and tissue level of trace element, stage, histological differentiation was observed. It was postulated that levels of trace elements may help in diagnosis and prognosis of disease.

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Year:  1994        PMID: 7829172

Source DB:  PubMed          Journal:  Indian J Med Sci        ISSN: 0019-5359


  11 in total

1.  Serum total oxidant/antioxidant status and trace element levels in breast cancer patients.

Authors:  Jia-Fu Feng; Ling Lu; Ping Zeng; Yun-Hong Yang; Jun Luo; Yu-Wei Yang; Dong Wang
Journal:  Int J Clin Oncol       Date:  2011-10-05       Impact factor: 3.402

2.  Determining Serum Zinc and Magnesium Levels in Hemodialysis Patients Could be Helpful for Clinicians.

Authors:  Fereshteh Ahmadipour; Soleiman Mahjoub; Mahdi Pouramir; Abbas Siahposht; Azam Afshar Naderi; Abdorrahim Absalan
Journal:  Indian J Clin Biochem       Date:  2016-08-27

3.  Changes in serum copper levels in patients with malignant diseases undergoing radiotherapy.

Authors:  H R Mali; S A Siddiqui; M Garg; R K Singh; M L Bhatt
Journal:  Indian J Clin Biochem       Date:  1998-01

4.  Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells.

Authors:  Kenyon G Daniel; Di Chen; Shirley Orlu; Qiuzhi Cindy Cui; Fred R Miller; Q Ping Dou
Journal:  Breast Cancer Res       Date:  2005-09-20       Impact factor: 6.466

5.  Selenium in serum and neoplastic tissue in breast cancer: correlation with CEA.

Authors:  K Charalabopoulos; A Kotsalos; A Batistatou; A Charalabopoulos; P Vezyraki; D Peschos; V Kalfakakou; A Evangelou
Journal:  Br J Cancer       Date:  2006-08-01       Impact factor: 7.640

6.  Copper depletion inhibits CoCl2-induced aggressive phenotype of MCF-7 cells via downregulation of HIF-1 and inhibition of Snail/Twist-mediated epithelial-mesenchymal transition.

Authors:  Shun Li; Jing Zhang; Hong Yang; Chunhui Wu; Xitong Dang; Yiyao Liu
Journal:  Sci Rep       Date:  2015-07-15       Impact factor: 4.379

7.  The Role of Copper (II) on Kininogen Binding to Tropomyosin in the Presence of a Histidine-Proline-Rich Peptide.

Authors:  Anna Maria Santoro; Stefania Zimbone; Antonio Magrì; Diego La Mendola; Giulia Grasso
Journal:  Int J Mol Sci       Date:  2020-12-08       Impact factor: 5.923

Review 8.  Selective Targeting of Cancer Cells by Copper Ionophores: An Overview.

Authors:  Valentina Oliveri
Journal:  Front Mol Biosci       Date:  2022-03-04

Review 9.  Copper metabolism as a unique vulnerability in cancer.

Authors:  Vinit C Shanbhag; Nikita Gudekar; Kimberly Jasmer; Christos Papageorgiou; Kamal Singh; Michael J Petris
Journal:  Biochim Biophys Acta Mol Cell Res       Date:  2020-10-20       Impact factor: 4.739

Review 10.  A systematic review and meta-analysis on the association of serum and tumor tissue iron and risk of breast cancer.

Authors:  Akram Sanagoo; Faezeh Kiani; Marzieh Saei Gharenaz; Fatemeh Sayehmiri; Fatemeh Koohi; Leila Jouybari; Majjid Dousti
Journal:  Caspian J Intern Med       Date:  2020
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