Literature DB >> 7827517

[Buruli's ulcer, a pathology little known in Benin. Apropos of 227 cases].

R Josse1, A Guédénon, J Aguiar, S Anagonou, C Zinsou, C Prost, J Foundohou, J E Touze.   

Abstract

Cutaneous Mycobacterium infection is an endemic disease in Mono, Ouémé and Zou districts in the south of Benin, where it seems rarely known. The authors are reporting the results of a clinical, bacteriological, epidemiological and therapeutical study about 227 patients. Children are the principal targets of this disease. Ulceration are often seen in a critical step (3 or 4) and acid-fast bacilli have been found from 189 of 227 patients tested by bacilloscopy (smear microscopy). Medical treatments (antituberculosis and antileprosis drugs) are still disappointing. Also when necessary, surgery is done (broad excision, skin transplant afterwards) with promising results. However, complications like deformities and flexion contractors can persist after surgical treatment. In the south Benin, Buruli's ulcers are one of the major public health problems.

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Year:  1994        PMID: 7827517

Source DB:  PubMed          Journal:  Bull Soc Pathol Exot        ISSN: 0037-9085


  6 in total

1.  Mycobacterium ulcerans infection (Buruli ulcer) on the face: a comparative analysis of 13 clinically suspected cases from the Democratic Republic of Congo.

Authors:  Delphin M Phanzu; Roger L Mahema; Patrick Suykerbuyk; Désiré-Hubert B Imposo; Linda F Lehman; Elie Nduwamahoro; Wayne M Meyers; Marleen Boelaert; Françoise Portaels
Journal:  Am J Trop Med Hyg       Date:  2011-12       Impact factor: 2.345

2.  Evaluation of PCR-restriction profile analysis and IS2404 restriction fragment length polymorphism and amplified fragment length polymorphism fingerprinting for identification and typing of Mycobacterium ulcerans and M. marinum.

Authors:  K Chemlal; G Huys; P A Fonteyne; V Vincent; A G Lopez; L Rigouts; J Swings; W M Meyers; F Portaels
Journal:  J Clin Microbiol       Date:  2001-09       Impact factor: 5.948

3.  Variability in 3' end of 16S rRNA sequence of Mycobacterium ulcerans is related to geographic origin of isolates.

Authors:  F Portaels; P A Fonteyene; H de Beenhouwer; P de Rijk; A Guédénon; J Hayman; M W Meyers
Journal:  J Clin Microbiol       Date:  1996-04       Impact factor: 5.948

4.  Characterization of an unusual Mycobacterium: a possible missing link between Mycobacterium marinum and Mycobacterium ulcerans.

Authors:  K Chemlal; G Huys; F Laval; V Vincent; C Savage; C Gutierrez; M-A Laneelle; J Swings; W M Meyers; M Daffe; F Portaels
Journal:  J Clin Microbiol       Date:  2002-07       Impact factor: 5.948

5.  Effect of oxygen on growth of Mycobacterium ulcerans in the BACTEC system.

Authors:  J C Palomino; A M Obiang; L Realini; W M Meyers; F Portaels
Journal:  J Clin Microbiol       Date:  1998-11       Impact factor: 5.948

Review 6.  Drugs for treating Buruli ulcer (Mycobacterium ulcerans disease).

Authors:  Rie R Yotsu; Marty Richardson; Norihisa Ishii
Journal:  Cochrane Database Syst Rev       Date:  2018-08-23
  6 in total

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