Literature DB >> 7827383

Abducent nerve paralysis during interferon alpha-2a therapy in a case of chronic active hepatitis C.

Y Fukumoto1, T Shigemitsu, N Kajii, R Omura, T Harada, K Okita.   

Abstract

A 59-year-old woman with chronic active hepatitis C was treated with recombinant human interferon alpha-2a. After three days of administration, the patient complained of diplopia with dizziness and head heaviness. Ophthalmic examinations revealed a disturbance of the movement of left eye ball to the outer side without any other neurological signs. The diplopia, which was diagnosed as abducent nerve paralysis, improved rapidly and reversed at about 6 weeks after discontinuation of interferon and during infusion of hydrocortisone. To our knowledge, this is the first report of abducent nerve paralysis associated with alpha-2a interferon.

Entities:  

Mesh:

Substances:

Year:  1994        PMID: 7827383     DOI: 10.2169/internalmedicine.33.637

Source DB:  PubMed          Journal:  Intern Med        ISSN: 0918-2918            Impact factor:   1.271


  7 in total

1.  Abducens palsy and Sjogren's syndrome induced by pegylated interferon therapy.

Authors:  Akio Oishi; Kazuaki Miyamoto; Satoshi Kashii; Nagahisa Yoshimura
Journal:  Br J Ophthalmol       Date:  2007-06       Impact factor: 4.638

2.  Side effects of interferon-alpha therapy.

Authors:  Stefan Sleijfer; Marjolein Bannink; Arthur R Van Gool; Wim H J Kruit; Gerrit Stoter
Journal:  Pharm World Sci       Date:  2005-12

Review 3.  Ocular side effects of anti-rheumatic medications: what a rheumatologist should know.

Authors:  V Peponis; V C Kyttaris; S E Chalkiadakis; S Bonovas; N M Sitaras
Journal:  Lupus       Date:  2010-02-09       Impact factor: 2.911

Review 4.  Interferon-alpha-2a. A review of its pharmacological properties and therapeutic use in the management of viral hepatitis.

Authors:  M Haria; P Benfield
Journal:  Drugs       Date:  1995-11       Impact factor: 9.546

Review 5.  Vasculitic complications of interferon-alpha treatment for chronic hepatitis C virus infection: case report and review of the literature.

Authors:  Wilke Beuthien; Hans-Ullrich Mellinghoff; Johannes von Kempis
Journal:  Clin Rheumatol       Date:  2005-06-30       Impact factor: 3.650

6.  Bell's palsy during interferon alpha 2a treatment in a case with Behçet uveitis.

Authors:  Fatime Nilüfer Yalçindağ; Cem Alay
Journal:  F1000Res       Date:  2013-11-15

Review 7.  Ocular side effects of antirheumatic medications: a qualitative review.

Authors:  Clara M Castillejo Becerra; Yue Ding; Beatrice Kenol; Andrew Hendershot; Alexa Simon Meara
Journal:  BMJ Open Ophthalmol       Date:  2020-01-07
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.