Literature DB >> 7825686

Combined phacoemulsification, posterior chamber intraocular lens implantation, and trabeculectomy with mitomycin C.

P M Munden1, W L Alward.   

Abstract

PURPOSE: We evaluated the effectiveness of combined phacoemulsification, posterior chamber intraocular lens implantation, and trabeculectomy with mitomycin C in patients with coexisting cataract and glaucoma.
METHODS: We conducted a retrospective review of the records of 21 consecutive patients who had combined phacoemulsification, posterior chamber intraocular lens implantation, and trabeculectomy with mitomycin C. Patients were selected for the combined procedure on the basis of the degree to which intraocular pressure was controlled, toleration of medical therapy, degree of glaucomatous optic nerve damage, and extent of visual impairment because of cataract. Nine (43%) of the 21 patients had previous incisional surgery and were at high risk of surgical failure. All patients had at least six months' follow-up. Sixteen (76%) of 21 patients had at least one year of follow-up.
RESULTS: The mean preoperative intraocular pressure was 20.8 +/- 5.0 mm Hg (range, 13 to 35 mm Hg), which decreased to a mean postoperative intraocular pressure of 15.1 +/- 3.1 mm Hg (range, 9 to 21 mm Hg) as measured at last follow-up (P = .0002). The intraocular pressure was controlled between 6 and 21 mm Hg) in all patients at last follow-up. Seventeen (81%) of 21 patients had a best-corrected visual acuity of 20/40 or better at last follow-up. No patient had a decrease in visual acuity after surgery. Fifteen (71%) of 21 patients were using no antiglaucoma medications at last follow-up. Four of the remaining six patients were using one medication, and two were using two medications. A hyphema (less than 1.0 mm) was seen in seven (33%) of 21 patients and was the most common postoperative complication. No patient had a postoperative wound or bleb leak or a shallow anterior chamber. No patient developed symptomatic hypotony.
CONCLUSIONS: The glaucoma triple procedure with adjunctive mitomycin C appears to be a safe and effective surgical technique for treating selected patients with coexisting cataract and glaucoma.

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Year:  1995        PMID: 7825686     DOI: 10.1016/s0002-9394(14)73809-7

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


  6 in total

1.  Early postoperative trabeculectomy leakage: incidence, time course, severity, and impact on surgical outcome.

Authors:  H W A Henderson; E Ezra; I E Murdoch
Journal:  Br J Ophthalmol       Date:  2004-05       Impact factor: 4.638

2.  Trabeculectomy augmented with mitomycin C application under the scleral flap.

Authors:  S Beatty; T Potamitis; S Kheterpal; E C O'Neill
Journal:  Br J Ophthalmol       Date:  1998-04       Impact factor: 4.638

3.  Sponge delivery variables and tissue levels of 5-fluorouracil.

Authors:  M R Wilkins; N L Occleston; A Kotecha; L Waters; P T Khaw
Journal:  Br J Ophthalmol       Date:  2000-01       Impact factor: 4.638

4.  Results of combined phacoemulsification and trabeculectomy with mitomycin C in pseudoexfoliation versus non-pseudoexfoliation glaucoma.

Authors:  Gennady Landa; Ayala Pollack; Rony Rachmiel; Amir Bukelman; Arie Marcovich; Miriam Zalish
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2005-07-08       Impact factor: 3.117

5.  Cataract extraction and lens implantation with and without trabeculectomy: an intrapatient comparison.

Authors:  J C Bobrow
Journal:  Trans Am Ophthalmol Soc       Date:  1998

6.  Surgically induced astigmatism following single site and twin site phacotrabeculectomy augmented with mitomycin C.

Authors:  Devendra Maheshwari; Ashwin Segi; Sarika Ramugade Shinde; Mohideen Abdul Kader; Ramakrishnan Rengappa
Journal:  Eye (Lond)       Date:  2021-06-11       Impact factor: 4.456

  6 in total

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