Literature DB >> 7822882

Centrally acting skeletal muscle relaxants and associated drugs.

H J Waldman1.   

Abstract

A review of available studies supports a role for muscle relaxants in the treatment of painful musculoskeletal disorders. The utility of these drugs is limited by sedation and other side effects, as well as by the potential for abuse and dependency. Other drugs can also be used in the treatment of muscle spasm, specifically diazepam, baclofen, dantrolene sodium, and quinine sulfate. The pharmacology of the muscle relaxants and these other agents is discussed and practical suggestions for use are offered.

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Year:  1994        PMID: 7822882     DOI: 10.1016/0885-3924(94)90199-6

Source DB:  PubMed          Journal:  J Pain Symptom Manage        ISSN: 0885-3924            Impact factor:   3.612


  5 in total

1.  Development of a capillary electrophoresis method for the determination of orphenadrine citrate in tablets in the presence of paracetamol.

Authors:  Dana N Haj-Ali; Imad I Hamdan
Journal:  Saudi Pharm J       Date:  2010-08-02       Impact factor: 4.330

2.  Anticonvulsant and related neuropharmacological effects of the whole plant extract of Synedrella nodiflora (L.) Gaertn (Asteraceae).

Authors:  Patrick Amoateng; Eric Woode; Samuel B Kombian
Journal:  J Pharm Bioallied Sci       Date:  2012-04

3.  Single and Multiple Dose PK-PD Characterization for Carisoprodol. Part I: Pharmacokinetics, Metabolites, and 2C19 Phenotype Influence. Double-Blind, Placebo-Controlled Clinical Trial in Healthy Volunteers.

Authors:  Aitana Calvo; Saioa Alonso; Esther Prieto; Ana Ascaso-Del-Rio; Jordi Ortuño; Nieves Fernandez; Antonio Portolés
Journal:  J Clin Med       Date:  2022-02-06       Impact factor: 4.241

4.  Carisoprodol Single and Multiple Dose PK-PD. Part II: Pharmacodynamics Evaluation Method for Central Muscle Relaxants. Double-Blind Placebo-Controlled Clinical Trial in Healthy Volunteers.

Authors:  Aitana Calvo; Mercedes González-Hidalgo; Ana Terleira; Nieves Fernández; Antonio Portolés
Journal:  J Clin Med       Date:  2022-02-21       Impact factor: 4.241

5.  Pilot study of orphenadrine as a novel treatment for muscle cramps in patients with liver cirrhosis.

Authors:  Sherief Abd-Elsalam; Ferial El-Kalla; Lobna A Ali; Samah Mosaad; Walaa Alkhalawany; Berihan Elemary; Rehab Badawi; Asmaa Elzeftawy; Amr Hanafy; Asem Elfert
Journal:  United European Gastroenterol J       Date:  2017-09-06       Impact factor: 4.623

  5 in total

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