Literature DB >> 7822119

Processing of Alzheimer A beta-amyloid precursor protein: cell biology, regulation, and role in Alzheimer disease.

S Gandy1, P Greengard.   

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Year:  1994        PMID： 7822119     DOI： 10.1016/s0074-7742(08)60302-5

Source DB:  PubMed          Journal:  Int Rev Neurobiol        ISSN： 0074-7742            Impact factor:   3.230


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  15 in total

Review 1.  The role of exosomes in the processing of proteins associated with neurodegenerative diseases.

Authors:  Laura J Vella; Robyn A Sharples; Rebecca M Nisbet; Roberto Cappai; Andrew F Hill
Journal:  Eur Biophys J       Date:  2007-12-07       Impact factor: 1.733

2.  Cholinergic Mechanisms in the Cerebral Cortex: Beyond Synaptic Transmission.

Authors:  Saak V Ovsepian; Valerie B O'Leary; Laszlo Zaborszky
Journal:  Neuroscientist       Date:  2015-05-22       Impact factor: 7.519

3.  Phorbol esters affect multiple steps in beta-amyloid precursor protein trafficking and amyloid beta-protein production.

Authors:  E H Koo
Journal:  Mol Med       Date:  1997-03       Impact factor: 6.354

4.  Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation.

Authors:  H Xu; D Sweeney; R Wang; G Thinakaran; A C Lo; S S Sisodia; P Greengard; S Gandy
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-15       Impact factor: 11.205

Review 5.  Beta-amyloid production, aggregation, and clearance as targets for therapy in Alzheimer's disease.

Authors:  Fernanda G De Felice; Sérgio T Ferreira
Journal:  Cell Mol Neurobiol       Date:  2002-12       Impact factor: 5.046

6.  Searching for disease modifiers-PKC activation and HDAC inhibition - a dual drug approach to Alzheimer's disease that decreases Abeta production while blocking oxidative stress.

Authors:  Alan P Kozikowski; Yihua Chen; Tapadar Subhasish; Nancy E Lewin; Peter M Blumberg; Zhenyu Zhong; Melissa A D'Annibale; Weng-Long Wang; Yong Shen; Brett Langley
Journal:  ChemMedChem       Date:  2009-07       Impact factor: 3.466

7.  Expression of Rab3A GTPase and other synaptic proteins is induced in differentiated NT2N neurons.

Authors:  K M Sheridan; W A Maltese
Journal:  J Mol Neurosci       Date:  1998-04       Impact factor: 3.444

8.  Enhanced generation of Alzheimer's amyloid-beta following chronic exposure to phorbol ester correlates with differential effects on alpha and epsilon isozymes of protein kinase C.

Authors:  Odete A B da Cruz e Silva; Sandra Rebelo; Sandra I Vieira; Sam Gandy; Edgar F da Cruz e Silva; Paul Greengard
Journal:  J Neurochem       Date:  2008-12-02       Impact factor: 5.372

Review 9.  Signal transduction therapeutics: relevance for Alzheimer's disease.

Authors:  Odete A B da Cruz e Silva; Margarida Fardilha; Ana Gabriela Henriques; Sandra Rebelo; Sandra Vieira; Edgar F da Cruz e Silva
Journal:  J Mol Neurosci       Date:  2004       Impact factor: 3.444

10.  Cyclopamine modulates γ-secretase-mediated cleavage of amyloid precursor protein by altering its subcellular trafficking and lysosomal degradation.

Authors:  Anna G Vorobyeva; Randall Lee; Sean Miller; Charles Longen; Michal Sharoni; Preeti J Kandelwal; Felix J Kim; Daniel R Marenda; Aleister J Saunders
Journal:  J Biol Chem       Date:  2014-10-03       Impact factor: 5.157
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