Literature DB >> 7821803

Cloning of cDNAs coding for the G alpha i1 and G alpha i2 G-proteins from chick brain.

E J Kilbourne1, J B Galper.   

Abstract

We have cloned and characterized several cDNAs coding for G-protein inhibitory alpha subunits (G alpha i) from a chick brain cDNA library. Based on homology to G alpha subunits from other eukaryotes, these clones were designated chick G alpha i1 and G alpha i2. On the deduced amino-acid level, G alpha i1 and G alpha i2 were found to be 98 and 95% identical to rat G alpha i1 and G alpha i2, respectively. Using RNase protection analysis, the G alpha i1 and G alpha i2 mRNAs were found to be expressed in chick atria, ventricle, lung, liver, brain and kidney.

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Year:  1994        PMID: 7821803     DOI: 10.1016/0378-1119(94)90449-9

Source DB:  PubMed          Journal:  Gene        ISSN: 0378-1119            Impact factor:   3.688


  1 in total

1.  Induction of the cholesterol metabolic pathway regulates the farnesylation of RAS in embryonic chick heart cells: a new role for ras in regulating the expression of muscarinic receptors and G proteins.

Authors:  A P Gadbut; L Wu; D Tang; A Papageorge; J A Watson; J B Galper
Journal:  EMBO J       Date:  1997-12-15       Impact factor: 11.598

  1 in total

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