Literature DB >> 7819719

Hepatocellular-cholestatic liver injury due to amoxycillin-clavulanic acid combination.

A Habior1, B Walewska-Zielecka, E Butruk.   

Abstract

Two cases (first cases from Poland and Eastern Europe) with liver injury due to amoxycillin-clavulanic acid (augmentin) are reported. Pruritus and jaundice were the main symptoms. Liver biopsy revealed mixed hepatocellular-cholestatic liver injury in both cases. In addition, in one case the microgranulomalike aggregate of inflammatory cells was found. Clinical and laboratory abnormalities returned to normal within 13 weeks.

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Year:  1994        PMID： 7819719     DOI： 10.1007/bf00227455

Source DB:  PubMed          Journal:  Clin Investig        ISSN： 0941-0198


  7 in total

1.  Cholestatic hepatitis associated with clavulanic acid.

Authors:  J Ryan; F Dudley
Journal:  Gut       Date:  1992-11       Impact factor: 23.059

2.  Granulomatous hepatitis due to combination of amoxicillin and clavulanic acid.

Authors:  C Silvain; E Fort; P Levillain; J Labat-Labourdette; M Beauchant
Journal:  Dig Dis Sci       Date:  1992-01       Impact factor: 3.199

3.  Cholestatic hepatitis after therapy with amoxicillin/clavulanate potassium.

Authors:  J E Schneider; M S Kleinman; J W Kupiec
Journal:  N Y State J Med       Date:  1989-06

4.  Hepatitis associated with amoxycillin-clavulanic acid combination report of 15 cases.

Authors:  D Larrey; T Vial; A Micaleff; G Babany; M Morichau-Beauchant; H Michel; J P Benhamou
Journal:  Gut       Date:  1992-03       Impact factor: 23.059

5.  Amoxicillin-clavulanate potassium-associated cholestasis.

Authors:  K R Reddy; P Brillant; E R Schiff
Journal:  Gastroenterology       Date:  1989-04       Impact factor: 22.682

Review 6.  Review article: drug-induced hepatotoxicity.

Authors:  W M Lee
Journal:  Aliment Pharmacol Ther       Date:  1993-10       Impact factor: 8.171

7.  Cholestatic hepatitis due to antibacterial combination of amoxicillin and clavulanic acid (augmentin)

Authors:  B H Stricker; J W Van den Broek; J Keuning; W Eberhardt; H G Houben; M Johnson; A P Blok
Journal:  Dig Dis Sci       Date:  1989-10       Impact factor: 3.199
  7 in total
  2 in total

Review 1.  Important elements for the diagnosis of drug-induced liver injury.

Authors:  Vijay K Agarwal; John G McHutchison; Jay H Hoofnagle
Journal:  Clin Gastroenterol Hepatol       Date:  2010-02-17       Impact factor: 11.382

Review 2.  Antibacterial-induced hepatotoxicity. Incidence, prevention and management.

Authors:  D K George; D H Crawford
Journal:  Drug Saf       Date:  1996-07       Impact factor: 5.606
  2 in total

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