| Literature DB >> 7816901 |
H Tsuchiya1, M Sato, M Akagiri, N Takagi, T Tanaka, M Iinuma.
Abstract
The antifungal activity of different synthetic hydroxychalcones was determined against Candida species. It was revealed that the presence of hydroxyl groups at C-2, C-4, and C-2' in chalcone was essential to inhibit Candida growth. Among the chalcone derivatives examined, 2,4,2'-trihydroxy-5'-methylchalcone showed the most intensive anti-Candida activity, suggesting that it could be a potential therapeutic agent for candidosis.Entities:
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Year: 1994 PMID： 7816901
Source DB: PubMed Journal: Pharmazie ISSN： 0031-7144 Impact factor: 1.267