| Literature DB >> 7815889 |
H Vrielink1, C L van der Poel, H W Reesink, H L Zaaijer, E Scholten, L C Kremer, H T Cuypers, P N Lelie, M H van Oers.
Abstract
The infectivity of blood components from donors who were later found to be anti-HCV ELISA-positive was investigated in recipients who were enrolled in a look-back programme. Recipients received ELISA-positive blood components from donors who were PCR-positive and/or RIBA-2-positive (n = 22, group A) or PCR-negative and indeterminate or negative on RIBA-2 (n = 105, group B). 26 of 32 (81%) recipients of group A donors and none of 140 of group B were HCV-infected. All stored serum samples of previous donations (n = 172) of group A donors were anti-HCV-positive in RIBA-3, indicating a chronic carrier state of HCV in these donors.Entities:
Mesh：
Year: 1995 PMID： 7815889 DOI： 10.1016/s0140-6736(95)90063-2
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321