Literature DB >> 78156

Down syndrome and thyroid function in adults.

R G Baxter, R G Larkins, F I Martin, P Heyma, K Myles, L Ryan.   

Abstract

Thyroid function has been studied in 11 middle-aged and elderly subjects with proven Down syndrome. Unequivaocal biochemical evidence of hypothyroidism was found in 6, and of thyrotoxicosis in 1. It is concluded that, in contrast to the situation in children with Down syndrome, thyroid dysfunction is exceedingly common in adults with the syndrome.

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Year:  1975        PMID： 78156     DOI： 10.1016/s0140-6736(75)80007-9

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  18 in total

1.  Down's syndrome and the general practitioner.

Authors:  G Howells
Journal:  Occas Pap R Coll Gen Pract       Date:  1990-11

2.  Consensus statement on management of hypothyroidism and hyperthyroidism. People with Down's syndrome should be screened.

Authors:  J Mcaloon
Journal:  BMJ       Date:  1996-12-07

3.  Are the medical needs of mentally handicapped adults being met?

Authors:  G Howells
Journal:  J R Coll Gen Pract       Date:  1986-10

4.  Cell-mediated cytotoxicity in Down syndrome: impairment of allogeneic mixed lymphocyte reaction, NK and NK-like activities.

Authors:  D Montagna; R Maccario; A G Ugazio; L Nespoli; E Pedroni; P Faggiano; G R Burgio
Journal:  Eur J Pediatr       Date:  1988-10       Impact factor: 3.183

5.  Lymphocyte subpopulations in Down's syndrome: high percentage of circulating HNK-1+, Leu 2a+ cells.

Authors:  R Maccario; A G Ugazio; L Nespoli; C Alberini; D Montagna; F Porta; F Bonetti; G R Burgio
Journal:  Clin Exp Immunol       Date:  1984-07       Impact factor: 4.330

6.  Autoimmune chronic active hepatitis in Down's syndrome.

Authors:  A J McCulloch; P G Ince; P Kendall-Taylor
Journal:  J Med Genet       Date:  1982-06       Impact factor: 6.318

7.  Down's syndrome and hypothyroidism.

Authors:  M W Quinn
Journal:  Ir J Med Sci       Date:  1980-01       Impact factor: 1.568

8.  Community study of hypothyroidism in Down's syndrome.

Authors:  E de H Lobo; M Khan; J Tew
Journal:  Br Med J       Date:  1980-05-24

9.  Evolved developmental homeostasis disturbed in LB1 from Flores, Indonesia, denotes Down syndrome and not diagnostic traits of the invalid species Homo floresiensis.

Authors:  Maciej Henneberg; Robert B Eckhardt; Sakdapong Chavanaves; Kenneth J Hsü
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-04       Impact factor: 11.205

10.  Thyroid dysfunction in Down's syndrome: relation to age and thyroid autoimmunity.

Authors:  B Karlsson; J Gustafsson; G Hedov; S A Ivarsson; G Annerén
Journal:  Arch Dis Child       Date:  1998-09       Impact factor: 3.791
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