| Literature DB >> 78155 |
R J Fallon, A W Lees, G W Allan, J Smith, W F Tyrrell.
Abstract
Serum-levels of rifampicin were investigated in patients receiving rifampicin alone or with other antituberculosis drugs. 2 g of probenecid given 30 min before 300 mg of rifampicin did not result in raising serum levels to more than half those achieved with the standard 600 mg dose of rifampicin. Hence probenecid should not be used to reduce rifampicin dosage in antituberculosis therapy.Entities:
Mesh：
Substances：
Year: 1975 PMID： 78155 DOI： 10.1016/s0140-6736(75)80006-7
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321