Literature DB >> 7814558

Analysis of hepatitis C virus isolates among healthy blood donors and drug addicts in Chiang Mai, Thailand.

C Apichartpiyakul1, C Chittivudikarn, H Miyajima, M Homma, H Hotta.   

Abstract

Hepatitis C virus (HCV) isolates obtained from 25 anti-HCV antibody-positive healthy blood donors and 29 drug addicts in Chiang Mai, Thailand, were analyzed. HCV RNA was detected in 23 blood donor samples (92%) and 24 drug addict blood samples (83%) by PCR for a portion of the NS5 region. Subtype analysis revealed that HCV type 3a (HCV-3a) was the prevailing subtype (30%), which was followed in prevalence by HCV-1a (21%), -1b (13%), -3b (13%), and -6a (2%). Six (13%) of the 47 isolates showed low sequence similarities with known types and subtypes. The sequence variants could be grouped into four branches in a molecular evolutionary phylogenetic tree.

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Year:  1994        PMID： 7814558      PMCID： PMC263982          DOI： 10.1128/jcm.32.9.2276-2279.1994

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  22 in total

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2.  Severity of liver disease with different hepatitis C viral clones.

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Review 4.  Molecular biology of the hepatitis C viruses: implications for diagnosis, development and control of viral disease.

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  9 in total

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Authors:  H Doi; C Apichartpiyakul; K I Ohba; M Mizokami; H Hotta
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5.  Genotypic distribution of hepatitis C virus in different regions of Thailand.

Authors:  D Kanistanon; M Neelamek; T Dharakul; S Songsivilai
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6.  Survey of type 6 group variants of hepatitis C virus in Southeast Asia by using a core-based genotyping assay.

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7.  Differential prevalence of hepatitis C virus subtypes in healthy blood donors, patients on maintenance hemodialysis, and patients with hepatocellular carcinoma in Surabaya, Indonesia.

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8.  Comparative sequence analysis of the core protein and its frameshift product, the F protein, of hepatitis C virus subtype 1b strains obtained from patients with and without hepatocellular carcinoma.

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  9 in total

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