Literature DB >> 7814338

Molecular cloning, DNA sequence analysis, and characterization of the Corynebacterium diphtheriae dtxR homolog from Brevibacterium lactofermentum.

J A Oguiza1, X Tao, A T Marcos, J F Martín, J R Murphy.   

Abstract

A homolog of the Corynebacterium diphtheriae dtxR gene was isolated from Brevibacterium lactofermentum. The product of the B. lactofermentum dtxR gene was immunoreactive with polyclonal anti-DtxR antibodies and functioned as an iron-activated repressor capable of regulating the expression of beta-galactosidase from a diphtheria tox promoter/operator transcriptional fusion in recombinant Escherichia coli. The extents of induction by increasing concentrations of the chelator 2,2'-dipyridyl were identical in cells expressing DtxR from either C. diphtheriae or B. lactofermentum.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7814338      PMCID： PMC176612          DOI： 10.1128/jb.177.2.465-467.1995

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  10 in total

1.  Molecular cloning and DNA sequence analysis of a diphtheria tox iron-dependent regulatory element (dtxR) from Corynebacterium diphtheriae.

Authors:  J Boyd; M N Oza; J R Murphy
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

2.  Determination of the minimal essential nucleotide sequence for diphtheria tox repressor binding by in vitro affinity selection.

Authors:  X Tao; J R Murphy
Journal:  Proc Natl Acad Sci U S A       Date:  1994-09-27       Impact factor: 11.205

3.  Specific binding of the diphtheria tox regulatory element DtxR to the tox operator requires divalent heavy metal ions and a 9-base-pair interrupted palindromic sequence.

Authors:  X Tao; J Boyd; J R Murphy
Journal:  Proc Natl Acad Sci U S A       Date:  1992-07-01       Impact factor: 11.205

4.  Characterization of a defective diphtheria toxin repressor (dtxR) allele and analysis of dtxR transcription in wild-type and mutant strains of Corynebacterium diphtheriae.

Authors:  M P Schmitt; R K Holmes
Journal:  Infect Immun       Date:  1991-11       Impact factor: 3.441

5.  Cloning, sequence, and footprint analysis of two promoter/operators from Corynebacterium diphtheriae that are regulated by the diphtheria toxin repressor (DtxR) and iron.

Authors:  M P Schmitt; R K Holmes
Journal:  J Bacteriol       Date:  1994-02       Impact factor: 3.490

6.  Characterization of mutations that inactivate the diphtheria toxin repressor gene (dtxR).

Authors:  Z Wang; M P Schmitt; R K Holmes
Journal:  Infect Immun       Date:  1994-05       Impact factor: 3.441

7.  DNA sequences and characterization of dtxR alleles from Corynebacterium diphtheriae PW8(-), 1030(-), and C7hm723(-).

Authors:  J M Boyd; K C Hall; J R Murphy
Journal:  J Bacteriol       Date:  1992-02       Impact factor: 3.490

Review 8.  Iron, DtxR, and the regulation of diphtheria toxin expression.

Authors:  X Tao; N Schiering; H Y Zeng; D Ringe; J R Murphy
Journal:  Mol Microbiol       Date:  1994-10       Impact factor: 3.501

9.  Iron-dependent regulation of diphtheria toxin and siderophore expression by the cloned Corynebacterium diphtheriae repressor gene dtxR in C. diphtheriae C7 strains.

Authors:  M P Schmitt; R K Holmes
Journal:  Infect Immun       Date:  1991-06       Impact factor: 3.441

10.  Characterization of an iron-regulated promoter involved in desferrioxamine B synthesis in Streptomyces pilosus: repressor-binding site and homology to the diphtheria toxin gene promoter.

Authors:  K Günter; C Toupet; T Schupp
Journal:  J Bacteriol       Date:  1993-06       Impact factor: 3.490
  10 in total
  21 in total

1.  Anion-coordinating residues at binding site 1 are essential for the biological activity of the diphtheria toxin repressor.

Authors:  J Goranson-Siekierke; E Pohl; W G Hol; R K Holmes
Journal:  Infect Immun       Date:  1999-04       Impact factor: 3.441

2.  Solution structure and peptide binding studies of the C-terminal src homology 3-like domain of the diphtheria toxin repressor protein.

Authors:  G Wang; G P Wylie; P D Twigg; D L Caspar; J R Murphy; T M Logan
Journal:  Proc Natl Acad Sci U S A       Date:  1999-05-25       Impact factor: 11.205

3.  Determinants of the SRC homology domain 3-like fold.

Authors:  J Alejandro D'Aquino; Dagmar Ringe
Journal:  J Bacteriol       Date:  2003-07       Impact factor: 3.490

4.  Identification and characterization of three new promoter/operators from Corynebacterium diphtheriae that are regulated by the diphtheria toxin repressor (DtxR) and iron.

Authors:  J H Lee; T Wang; K Ault; J Liu; M P Schmitt; R K Holmes
Journal:  Infect Immun       Date:  1997-10       Impact factor: 3.441

5.  Characterization of specific nucleotide substitutions in DtxR-specific operators of Corynebacterium diphtheriae that dramatically affect DtxR binding, operator function, and promoter strength.

Authors:  J H Lee; R K Holmes
Journal:  J Bacteriol       Date:  2000-01       Impact factor: 3.490

6.  Multiple sigma factor genes in Brevibacterium lactofermentum: characterization of sigA and sigB.

Authors:  J A Oguiza; A T Marcos; M Malumbres; J F Martín
Journal:  J Bacteriol       Date:  1996-01       Impact factor: 3.490

7.  The DtxR regulon of Corynebacterium glutamicum.

Authors:  Julia Wennerhold; Michael Bott
Journal:  J Bacteriol       Date:  2006-04       Impact factor: 3.490

8.  SirR, a novel iron-dependent repressor in Staphylococcus epidermidis.

Authors:  P J Hill; A Cockayne; P Landers; J A Morrissey; C M Sims; P Williams
Journal:  Infect Immun       Date:  1998-09       Impact factor: 3.441

9.  Characterization of an iron-dependent regulatory protein (IdeR) of Mycobacterium tuberculosis as a functional homolog of the diphtheria toxin repressor (DtxR) from Corynebacterium diphtheriae.

Authors:  M P Schmitt; M Predich; L Doukhan; I Smith; R K Holmes
Journal:  Infect Immun       Date:  1995-11       Impact factor: 3.441

10.  Response of the cytoplasmic and membrane proteome of Corynebacterium glutamicum ATCC 13032 to pH changes.

Authors:  Mónica Barriuso-Iglesias; Daniela Schluesener; Carlos Barreiro; Ansgar Poetsch; Juan F Martín
Journal:  BMC Microbiol       Date:  2008-12-17       Impact factor: 3.605
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.