Literature DB >> 7814287

In-vitro activity of new sulphanilil fluoroquinolones against Staphylococcus aureus.

D A Allemandi1, F L Alovero, R H Manzo.   

Abstract

Two new quinolones, NSFQ-104 and NSFQ-105, derivatives of ciprofloxacin and norfloxacin with a 4-(4-aminophenylsulphonyl)-1-piperazinyl at position 7 showed better in-vitro activity against strains of methicillin-susceptible and methicillin-resistant Staphylococcus aureus than ciprofloxacin or norfloxacin. Their in-vitro activity was enhanced at pH 5.5.

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Year:  1994        PMID： 7814287     DOI： 10.1093/jac/34.2.261

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  5 in total

1.  Activity of newer fluoroquinolones in vitro against gram-positive bacteria.

Authors:  G M Eliopoulos
Journal:  Drugs       Date:  1999       Impact factor: 9.546

2.  Engineering the specificity of antibacterial fluoroquinolones: benzenesulfonamide modifications at C-7 of ciprofloxacin change its primary target in Streptococcus pneumoniae from topoisomerase IV to gyrase.

Authors:  F L Alovero; X S Pan; J E Morris; R H Manzo; L M Fisher
Journal:  Antimicrob Agents Chemother       Date:  2000-02       Impact factor: 5.191

3.  Contrasting effects of acidic pH on the extracellular and intracellular activities of the anti-gram-positive fluoroquinolones moxifloxacin and delafloxacin against Staphylococcus aureus.

Authors:  Sandrine Lemaire; Paul M Tulkens; Françoise Van Bambeke
Journal:  Antimicrob Agents Chemother       Date:  2010-12-06       Impact factor: 5.191

4.  Mode of action of sulfanilyl fluoroquinolones.

Authors:  F Alovero; M Nieto; M R Mazzieri; R Then; R H Manzo
Journal:  Antimicrob Agents Chemother       Date:  1998-06       Impact factor: 5.191

5.  Synthesis, Antibacterial Evaluation and QSAR of α-Substituted-N₄-Acetamides of Ciprofloxacin and Norfloxacin.

Authors:  Amjad M Qandil; Lorca O Al-Zoubi; Amal G Al-Bakri; Haneen A Amawi; Qosay A Al-Balas; Abdulmalik M Alkatheri; Abdulkareem M Albekairy
Journal:  Antibiotics (Basel)       Date:  2014-06-25
  5 in total

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