Literature DB >> 7814253

A comparison of sensitivity analysis techniques.

D M Hamby1.   

Abstract

Modeling the movement and consequence of radioactive pollutants is critical for environmental protection and control of nuclear facilities. Sensitivity analysis is an integral part of model development and involves analytical examination of input parameters to aid in model validation and provide guidance for future research. Sensitivities of 21 input parameters have been analyzed for a specific-activity tritium dose model using fourteen methods of parameter sensitivity analysis. This report demonstrates, for each sensitivity method, the required calculational effort, the sensitivity ranking of parameters, and the relative method performance. The sensitivity measures include the following: partial derivatives, variation of inputs by 1 standard deviation (SD) and by 20%, a sensitivity index, an importance index, a relative deviation of the output distribution, a relative deviation ratio, partial rank correlation coefficients, standardized regression coefficients, rank regression coefficients, the Smirnov test, the Cramer-von Mises test, the Mann-Whitney test, and the squared-ranks test.

Entities:  

Mesh:

Substances:

Year:  1995        PMID: 7814253     DOI: 10.1097/00004032-199502000-00005

Source DB:  PubMed          Journal:  Health Phys        ISSN: 0017-9078            Impact factor:   1.316


  17 in total

1.  Partial derivative-based sensitivity analysis of models describing target-mediated drug disposition.

Authors:  Anson K Abraham; Wojciech Krzyzanski; Donald E Mager
Journal:  AAPS J       Date:  2007-06-08       Impact factor: 4.009

Review 2.  Sensitivity analysis of infectious disease models: methods, advances and their application.

Authors:  Jianyong Wu; Radhika Dhingra; Manoj Gambhir; Justin V Remais
Journal:  J R Soc Interface       Date:  2013-07-17       Impact factor: 4.118

3.  Sensitivity analysis of an electrophysiology model for the left ventricle.

Authors:  Giulio Del Corso; Roberto Verzicco; Francesco Viola
Journal:  J R Soc Interface       Date:  2020-10-28       Impact factor: 4.118

4.  An analytical approach for estimating uncertainty in measured temperatures of concrete slab during fire.

Authors:  Dilip K Banerjee
Journal:  Fire Saf J       Date:  2016       Impact factor: 2.764

5.  Use of a local sensitivity analysis to inform study design based on a mechanistic toxicokinetic model for γ-hydroxybutyric acid.

Authors:  Melanie A Felmlee; Wojciech Krzyzanski; Bridget L Morse; Marilyn E Morris
Journal:  AAPS J       Date:  2011-03-09       Impact factor: 4.009

6.  Benefits and costs of substance abuse treatment programs for state prison inmates: results from a lifetime simulation model.

Authors:  Gary A Zarkin; Alexander J Cowell; Katherine A Hicks; Michael J Mills; Steven Belenko; Laura J Dunlap; Kimberly A Houser; Vince Keyes
Journal:  Health Econ       Date:  2011-04-19       Impact factor: 3.046

7.  Multiscale Model of Mycobacterium tuberculosis Infection Maps Metabolite and Gene Perturbations to Granuloma Sterilization Predictions.

Authors:  Elsje Pienaar; William M Matern; Jennifer J Linderman; Joel S Bader; Denise E Kirschner
Journal:  Infect Immun       Date:  2016-04-22       Impact factor: 3.441

8.  Parameter uncertainty and sensitivity in a liquid-effluent dose model.

Authors:  T C Hyman; D M Hamby
Journal:  Environ Monit Assess       Date:  1995-10       Impact factor: 2.513

9.  Physiologically-based pharmacokinetic (PBPK) model to predict IgG tissue kinetics in wild-type and FcRn-knockout mice.

Authors:  Amit Garg; Joseph P Balthasar
Journal:  J Pharmacokinet Pharmacodyn       Date:  2007-07-18       Impact factor: 2.745

10.  Cell membrane water exchange effects in prostate DCE-MRI.

Authors:  Xin Li; Ryan A Priest; William J Woodward; Faisal Siddiqui; Tomasz M Beer; Mark G Garzotto; William D Rooney; Charles S Springer
Journal:  J Magn Reson       Date:  2012-03-28       Impact factor: 2.229

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.