Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Increased frequency of micronuclei in lymphocytes of Swedish chimney sweeps.

Literature DB >> 7814098

Increased frequency of micronuclei in lymphocytes of Swedish chimney sweeps.

A Holmén¹, A Karlsson, I Bratt, G Raihle, B Högstedt.

Abstract

Forty-five Swedish chimney sweeps and 49 controls were investigated with micronuclei stimulated by phytohemagglutinin and pokeweed mitogen and by analysis of lymphocyte subgroups and neutrophilic leukocytes. There was a statistically significant effect among sweeps with respect to both micronuclei variables and neutrophilic leukocytes. The effect on lymphocyte micronuclei was most prominent in pokeweed mitogen-stimulated cells, which may imply that the T4 lymphocytes were preferentially damaged by the occupational exposure.

Entities: Species

Mesh：

Substances：
Asbestos
Benzo(a)pyrene

Year: 1994 PMID： 7814098 DOI： 10.1007/bf00380778

Source DB: PubMed Journal: Int Arch Occup Environ Health ISSN： 0340-0131 Impact factor: 3.015

Keyword Cloud
References

12 in total

1. Gasoline pump mechanics had increased frequencies and sizes of micronuclei in lymphocytes stimulated by pokeweed mitogen.

Authors: B Högstedt; A Holmén; A Karlsson; G Raihle; K Nillius; K Vestlund
Journal: Mutat Res Date: 1991-05 Impact factor: 2.433

2. Cytogenetic effects in rotogravure printers exposed to toluene (and benzene).

Authors: G Nise; B Högstedt; I Bratt; S Skerfving
Journal: Mutat Res Date: 1991-11 Impact factor: 2.433

3. Mitotic cells in different lymphocyte subsets in unfractionated cultures stimulated by phytohaemagglutinin or pokeweed mitogen.

Authors: P E Kovanen; S Knuutila
Journal: Hereditas Date: 1989 Impact factor: 3.271

7. Frequency and size distribution of micronuclei in lymphocytes stimulated with phytohemagglutinin and pokeweed mitogen in workers exposed to piperazine.

Authors: B Högstedt; I Bratt; A Holmén; L Hagmar; S Skerfving
Journal: Hereditas Date: 1988 Impact factor: 3.271

Increased frequency of micronuclei in lymphocytes of Swedish chimney sweeps.

1. Gasoline pump mechanics had increased frequencies and sizes of micronuclei in lymphocytes stimulated by pokeweed mitogen.

2. Cytogenetic effects in rotogravure printers exposed to toluene (and benzene).

3. Mitotic cells in different lymphocyte subsets in unfractionated cultures stimulated by phytohaemagglutinin or pokeweed mitogen.

4. The Hemalog D white cell differential system.

5. Subtyping lymphocytes in peripheral blood by immunoperoxidase labeling and light scatter/absorption flow cytometry.

6. Some experimental design and analysis considerations for cytogenetics studies.

7. Frequency and size distribution of micronuclei in lymphocytes stimulated with phytohemagglutinin and pokeweed mitogen in workers exposed to piperazine.

8. Micronuclei in lymphocytes with preserved cytoplasm. A method for assessment of cytogenetic damage in man.

9. Excess of cancer in Swedish chimney sweeps.

10. Excess mortality among Swedish chimney sweeps.