Literature DB >> 7813478

A novel form of mouse cytochrome P450 3A (Cyp3a-16). Its cDNA cloning and expression in fetal liver.

S Itoh1, M Satoh, Y Abe, H Hashimoto, T Yanagimoto, T Kamataki.   

Abstract

A complementary DNA clone coding for a novel form of cytochrome P450, Cyp3a-16, in mouse fetal livers was isolated and completely sequenced. This clone encoded a polypeptide of 504 deduced amino acids and showed 87.3% and 66.6% amino acid identities with mouse Cyp3a-11 and Cyp3a-13, respectively. Cyp3a-16 transcript was detectable before birth and remarkably diminished five weeks after birth in mice. We conclude that Cyp3a-16 is a fetal- and puberty-specific cytochrome P450 in mice.

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Year:  1994        PMID: 7813478     DOI: 10.1111/j.1432-1033.1994.t01-1-00877.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN: 0014-2956


  4 in total

1.  A PCR primer bank for quantitative gene expression analysis.

Authors:  Xiaowei Wang; Brian Seed
Journal:  Nucleic Acids Res       Date:  2003-12-15       Impact factor: 16.971

2.  The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver.

Authors:  Stephanie C Casey; Bruce Blumberg
Journal:  Mol Endocrinol       Date:  2012-04-11

3.  Identification, induction and localization of cytochrome P450s of the 3A-subfamily in mouse brain.

Authors:  H Rosenbrock; C E Hagemeyer; M Ditter; R Knoth; B Volk
Journal:  Neurotox Res       Date:  2001-08       Impact factor: 3.911

4.  P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.

Authors:  E G Schuetz; A H Schinkel; M V Relling; J D Schuetz
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-30       Impact factor: 11.205

  4 in total

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