Literature DB >> 7811564

Impaired hepatic function in segmental biliary obstruction demonstrated with a receptor-binding radiotracer.

Y Inoue1, K Machida, N Honda, T Mamiya, T Takahashi, T Kamano, Y Sasaki.   

Abstract

A patient with cholangiocarcinoma underwent left-sided cholangiojejunostomy, and hepatic functional imaging with a receptor-binding radiotracer and SPECT was performed to evaluate the distribution of functional reserve. It revealed decreased accumulation in the regions with residual dilatation of the intrahepatic bile ducts, indicating several kinds of focal damage in hepatic function caused by segmental biliary obstruction. The radioligand may be useful in assessing regional hepatic function, and the high spatial resolution provided by SPECT appears to play an important role for this purpose.

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Year:  1994        PMID： 7811564     DOI： 10.1007/bf03164999

Source DB:  PubMed          Journal:  Ann Nucl Med        ISSN： 0914-7187            Impact factor:   2.668


  12 in total

1.  Functional hepatic imaging with receptor-binding radiopharmaceutical: clinical potential as a measure of functioning hepatocyte mass.

Authors:  M Kudo; A Todo; K Ikekubo; M Hino; Y Yonekura; K Yamamoto; K Torizuka
Journal:  Gastroenterol Jpn       Date:  1991-12

2.  Hepatic recognition and catabolism of serum glycoproteins.

Authors:  G Ashwell; C J Steer
Journal:  JAMA       Date:  1981-11-20       Impact factor: 56.272

Review 3.  Hepatic binding protein: the galactose-specific receptor of mammalian hepatocytes.

Authors:  R J Stockert; A G Morell
Journal:  Hepatology       Date:  1983 Sep-Oct       Impact factor: 17.425

4.  Scintigraphic detection of segmental bile-duct obstruction.

Authors:  S Gupta; D Owshalimpur; G Cohen; R Margules; N Herrera
Journal:  J Nucl Med       Date:  1982-10       Impact factor: 10.057

5.  Discordant hepatic uptake of Tc-99m NGA and Tc-99m PMT in a patient with hepatoma.

Authors:  T Aburano; N Shuke; K Yokoyama; N Tonami; K Hisada; M Tanei; M Terada; M Unoura; K Kobayashi
Journal:  Clin Nucl Med       Date:  1992-10       Impact factor: 7.794

6.  Tc-99m galactosyl-neoglycoalbumin: in vitro characterization of receptor-mediated binding.

Authors:  D R Vera; K A Krohn; R C Stadalnik; P O Scheibe
Journal:  J Nucl Med       Date:  1984-07       Impact factor: 10.057

7.  Sequential scintiphotography with technetium-99m pyridoxylideneglutamate in the detection of intrahepatic lithiasis: concise communication.

Authors:  S H Yeh; O K Liu; M J Huang
Journal:  J Nucl Med       Date:  1980-01       Impact factor: 10.057

8.  TC-99m(Sn)-N-pyridoxylaminates: a new series of hepatobiliary imaging agents.

Authors:  M Kato-Azuma
Journal:  J Nucl Med       Date:  1982-06       Impact factor: 10.057

9.  A quantitative model of technetium-99m-DTPA-galactosyl-HSA for the assessment of hepatic blood flow and hepatic binding receptor.

Authors:  S K Ha-Kawa; Y Tanaka
Journal:  J Nucl Med       Date:  1991-12       Impact factor: 10.057

10.  Decreased hepatic function in patients with hepatoma or liver metastasis monitored by a hepatocyte specific galactosylated radioligand.

Authors:  I Virgolini; C Müller; W Klepetko; P Angelberger; H Bergmann; J O'Grady; H Sinzinger
Journal:  Br J Cancer       Date:  1990-06       Impact factor: 7.640
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  2 in total

1.  Evaluation of regional liver damage by magnetic resonance imaging with superparamagnetic iron oxide in rat liver.

Authors:  T Murakami; T Kim; M Takamura; J Shimizu; M Hori; K Dono; K Takachi; N Kato; T Miyazawa; M Sakon; M Monden; H Nakamura
Journal:  Dig Dis Sci       Date:  2001-01       Impact factor: 3.199

2.  Evaluation of regional liver function by gadolinium-EOB-DTPA-enhanced MR imaging.

Authors:  J Shimizu; K Dono; M Gotoh; Y Hasuike; T Kim; T Murakami; M Sakon; K Umeshita; H Nagano; S Nakamori; N Kato; T Miyazawa; H Nakamura; M Monden
Journal:  Dig Dis Sci       Date:  1999-07       Impact factor: 3.199
  2 in total

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