Literature DB >> 7810895

Analysis of double-stranded oligonucleotides by electrospray mass spectrometry.

E Bayer1, T Bauer, K Schmeer, K Bleicher, M Maier, H J Gaus.   

Abstract

Double-stranded oligonucleotides of different lengths and chemical modification have been analyzed by ion spray mass spectrometry. The non-covalent-bonded duplexes can be detected. Therefore, ion spray mass spectrometry is a useful method for investigation of hybridizations of natural and chemically modified oligonucleotides. Since the exact mass of the double strand can be detected, this method can distinguish between specific and nonspecific interaction.

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Year:  1994        PMID： 7810895     DOI： 10.1021/ac00094a004

Source DB:  PubMed          Journal:  Anal Chem        ISSN： 0003-2700            Impact factor:   6.986


  13 in total

1.  Solution composition and thermal denaturation for the production of single-stranded PCR amplicons: piperidine-induced destabilization of the DNA duplex?

Authors:  John B Mangrum; Jason W Flora; David C Muddiman
Journal:  J Am Soc Mass Spectrom       Date:  2002-03       Impact factor: 3.109

2.  Activation energies for dissociation of double strand oligonucleotide anions: evidence for watson-crick base pairing in vacuo.

Authors:  P D Schnier; J S Klassen; E F Strittmatter; E R Williams
Journal:  J Am Chem Soc       Date:  1998-09-23       Impact factor: 15.419

3.  Gas-phase stability of double-stranded oligodeoxynucleotides and their noncovalent complexes with DNA-binding drugs as revealed by collisional activation in an ion trap.

Authors:  K X Wan; M L Gross; T Shibue
Journal:  J Am Soc Mass Spectrom       Date:  2000-05       Impact factor: 3.109

4.  Optimized suppression of adducts in polymerase chain reaction products for semi-quantitative SNP genotyping by liquid chromatography-mass spectrometry.

Authors:  Herbert Oberacher; Walther Parson; Georg Hölzl; Peter J Oefner; Christian G Huber
Journal:  J Am Soc Mass Spectrom       Date:  2004-12       Impact factor: 3.109

5.  Characterization of noncovalent complexes formed between minor groove binding molecules and duplex DNA by electrospray ionization-mass spectrometry.

Authors:  D C Galefn; R D Smithcor
Journal:  J Am Soc Mass Spectrom       Date:  1995-12       Impact factor: 3.109

6.  Tandem mass spectrometry of metal nitrate negative ions produced by electrospray ionization.

Authors:  Fumin Li; Matthew A Byers; R S Houk
Journal:  J Am Soc Mass Spectrom       Date:  2003-06       Impact factor: 3.109

7.  A role for the MS analysis of nucleic acids in the post-genomics age.

Authors:  Daniele Fabris
Journal:  J Am Soc Mass Spectrom       Date:  2009-09-17       Impact factor: 3.109

8.  OMA and OPA--software-supported mass spectra analysis of native and modified nucleic acids.

Authors:  Adrien Nyakas; Lorenz C Blum; Silvan R Stucki; Jean-Louis Reymond; Stefan Schürch
Journal:  J Am Soc Mass Spectrom       Date:  2012-12-21       Impact factor: 3.109

9.  Comparative stability determination of oligonucleotide duplexes in gas and solution phase.

Authors:  Mei Monica Yang; Richard Thompson; Gene Hall
Journal:  J Am Soc Mass Spectrom       Date:  2004-09       Impact factor: 3.262

10.  Collision-induced dissociation of bradykinin ions in the interface region of an ESI-MS.

Authors:  B B Schneider; D J Douglas; D D Chen
Journal:  J Am Soc Mass Spectrom       Date:  2001-07       Impact factor: 3.262
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